Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 6/20 | 0.50 |
| ▸ | NMT2 | O60551 | 5/20 | 0.50 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | CHRND | Q07001 | 5/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNG | P07510 | 1/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23314723 | 0.93 | NMT1 (0.52) | NMT1NMT2SIRT6SIRT1SLC6A5 | |
| SCHEMBL21541320 | 0.89 | NMT1 (0.50) | NMT1NMT2SIRT6SIRT1SLC6A5 | |
| SCHEMBL23736233 | 0.87 | NMT1 (0.50) | NMT1NMT2SIRT6SIRT1SLC6A5 | |
| SCHEMBL20357606 | 0.86 | SLC6A5 (0.51) | NMT1NMT2SIRT6SIRT1SLC6A5 | |
| SCHEMBL18067361 | 0.86 | NMT1 (0.45) | NMT1NMT2SIRT6SIRT1SLC6A5 | |
| SCHEMBL27345758 | 0.85 | NMT1 (0.47) | NMT1NMT2SIRT6SIRT1SLC6A5 | |
| SCHEMBL7284768 | 0.84 | SIRT6 (0.46) | NMT1NMT2SIRT6SIRT1SLC6A5 | |
| SCHEMBL23314862 | 0.82 | NMT1 (0.43) | NMT1NMT2SIRT6SIRT1SLC6A5 | |
| SCHEMBL21944205 | 0.81 | SIRT6 (0.47) | NMT1NMT2SIRT6SIRT1TLR2 | |
| SCHEMBL16976133 | 0.80 | SLC6A5 (0.62) | NMT1NMT2SIRT6SIRT1SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3145944-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2021-05-05 | — | — | EP | disclosed |