Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.45 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.45 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5902012 | 0.92 | NAAA (0.59) | EPHX2ITGB3ITGA2BNAAAPRMT1 | |
| SCHEMBL9830399 | 0.92 | PRMT1 (0.59) | EPHX2ITGB3ITGA2BNAAAPRMT1 | |
| SCHEMBL7739813 | 0.91 | NAAA (0.46) | EPHX2ITGB3ITGA2BNAAAPRMT1 | |
| SCHEMBL7739816 | 0.91 | NAAA (0.46) | EPHX2ITGB3ITGA2BNAAAPRMT1 | |
| SCHEMBL6502279 | 0.90 | NAAA (0.62) | EPHX2ITGB3ITGA2BNAAAEPHX1 | |
| SCHEMBL2678008 | 0.90 | NAAA (0.62) | EPHX2ITGB3ITGA2BNAAAEPHX1 | |
| SCHEMBL12849676 | 0.88 | EPHX2 (0.46) | EPHX2ITGB3ITGA2BNAAAPRMT1 | |
| SCHEMBL9831292 | 0.86 | NAAA (0.62) | EPHX2ITGB3ITGA2BNAAAPRMT1 | |
| SCHEMBL7740129 | 0.85 | NAAA (0.49) | EPHX2ITGB3ITGA2BNAAAGNAI3 | |
| SCHEMBL7740128 | 0.85 | NAAA (0.49) | EPHX2ITGB3ITGA2BNAAAGNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011095218-A1 | TEMPLATE-FIXED PEP TIDOMIME TICS WITH CXCR7 MODULATING ACTIVITY | POLYPHOR AG (CH) | 2011-08-11 | — | — | WO | disclosed |