Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 2/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3155441 | 0.88 | NFE2L2 (0.50) | MEN1KMT2ANFE2L2 | |
| SCHEMBL28374076 | 0.87 | GBA1 (0.63) | GBA1SLC18A3PRMT3CARM1PRMT6 | |
| SCHEMBL29013918 | 0.87 | GBA1 (0.63) | GBA1SLC18A3PRMT3CARM1PRMT6 | |
| SCHEMBL1119456 | 0.87 | GBA1 (0.63) | GBA1SLC18A3PRMT3CARM1PRMT6 | |
| SCHEMBL158625 | 0.87 | GBA1 (0.63) | GBA1SLC18A3PRMT3CARM1PRMT6 | |
| SCHEMBL8137977 | 0.87 | GBA1 (0.63) | GBA1SLC18A3PRMT3CARM1PRMT6 | |
| SCHEMBL113380 | 0.87 | GBA1 (0.63) | GBA1SLC18A3PRMT3CARM1PRMT6 | |
| SCHEMBL6290794 | 0.87 | GBA1 (0.63) | GBA1SLC18A3PRMT3CARM1PRMT6 | |
| SCHEMBL7438487 | 0.85 | NFE2L2 (0.47) | GBA1MEN1KMT2ANFE2L2 | |
| Ammonia Solution, Strong SCHEMBL2283846 | 0.85 | GBA1 (0.61) | GBA1SLC18A3PRMT3CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3816153-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2021-05-05 | — | — | EP | disclosed |