Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.42 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.42 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969138 | 0.90 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2CNR1POLB | |
| SCHEMBL11688541 | 0.87 | ESR1 (0.49) | HPGDTSHRPDE3BPDE3AP2RY12 | |
| SCHEMBL7660524 | 0.86 | HDAC3 (0.47) | HPGDPDE3BPDE3AP2RY12 | |
| SCHEMBL11857488 | 0.86 | MAPT (0.47) | HPGDNPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL7761596 | 0.85 | EPHX2 (0.49) | NPC1RAB9ASMN1; SMN2EPHX2POLB | |
| SCHEMBL22921868 | 0.84 | TSHR (0.58) | TSHREPHX2CYP4Z1CYP4F11CYP4F12 | |
| SCHEMBL2091468 | 0.81 | SKP2 (0.44) | HPGDCNR1 | |
| SCHEMBL1928824 | 0.81 | PLAAT3 (0.51) | TSHREPHX2CYP4Z1CYP4F11CYP4F12 | |
| SCHEMBL1453481 | 0.81 | CYP1A2 (0.57) | SMN1; SMN2TSHR | |
| SCHEMBL9861891 | 0.80 | TSHR (0.45) | HPGDTSHREPHX2CYP4Z1CYP4F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3816156-A1 | RADIOACTIVE COMPOUND FOR TREATMENT OF MELANOMA AND USE THEREOF | Industry Foundation of Chonnam National University (KR) | 2021-05-05 | — | — | EP | disclosed |