Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23315526 | 0.90 | HPGD (0.48) | NPC1RAB9ASMN1; SMN2CYP4F2CYP4A11 | |
| Phenyl Propionic Acid SCHEMBL28555657 | 0.88 | FFAR4 (0.58) | PTPN1FFAR4FFAR1 | |
| SCHEMBL12370801 | 0.87 | HRH3 (0.49) | NPC1RAB9ASMN1; SMN2PTPN1CYP4F2 | |
| SCHEMBL27972225 | 0.86 | APP (0.51) | PTPN1CYP4F2CYP4A11ALOX5OR51E2 | |
| SCHEMBL18269500 | 0.86 | ALOX5 (0.53) | PTPN1CYP4F2CYP4A11ALOX5OR51E2 | |
| SCHEMBL29901118 | 0.85 | CYP4F2 (0.45) | NPC1RAB9ASMN1; SMN2PTPN1CYP4F2 | |
| SCHEMBL1255726 | 0.85 | PTPN1 (0.46) | PTPN1CYP4F2CYP4A11ALOX5OR51E2 | |
| SCHEMBL14461366 | 0.85 | RAB9A (0.48) | RAB9APTPN1CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL18744079 | 0.85 | ALOX5 (0.55) | SMN1; SMN2ALOX5OR51E2POLBALDH1A1 | |
| SCHEMBL14901973 | 0.85 | PTPN1 (0.43) | NPC1RAB9ASMN1; SMN2PTPN1CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492887-A | HYDROFORMYLATION; REDUCTION; OXIDATION; HYDROGENATION; SEPARATION; INCREASING EXO/ENDO RATIO USING BASE CATALYSIS | DRAGOCO GERBERDING & CO. GMBH (DE) | 1996-02-20 | — | — | US | disclosed |