Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23315584 | 0.93 | SMN1; SMN2 (0.56) | RAB9APDE7ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL23315522 | 0.80 | ALOX15 (0.48) | RAB9ANPC1PDE7ASMN1; SMN2ALDH1A1 | |
| SCHEMBL23260964 | 0.79 | PDE7A (0.46) | PDE7ASMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL30074571 | 0.78 | ALOX15 (0.48) | PDE7ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL30074581 | 0.78 | ALOX15 (0.48) | PDE7ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL21531023 | 0.78 | ALOX15 (0.48) | PDE7ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL21531034 | 0.75 | CYP1A2 (0.57) | SMN1; SMN2LMNAALDH1A1KDM4EGAA | |
| SCHEMBL23293634 | 0.75 | ALOX15 (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL30074608 | 0.75 | ALOX15 (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL30074614 | 0.75 | ALOX15 (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3816156-A1 | RADIOACTIVE COMPOUND FOR TREATMENT OF MELANOMA AND USE THEREOF | Industry Foundation of Chonnam National University (KR) | 2021-05-05 | — | — | EP | disclosed |