Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30074581 | 0.82 | ALOX15 (0.48) | ALOX15PDE7APOLBMAPK1ALDH1A1 | |
| SCHEMBL21531023 | 0.82 | ALOX15 (0.48) | ALOX15PDE7APOLBMAPK1ALDH1A1 | |
| SCHEMBL30074571 | 0.82 | ALOX15 (0.48) | ALOX15PDE7APOLBMAPK1ALDH1A1 | |
| SCHEMBL23315586 | 0.80 | RAB9A (0.50) | PDE7AALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL30074614 | 0.79 | ALOX15 (0.48) | ALOX15POLBMAPK1ALDH1A1MAOB | |
| SCHEMBL21531034 | 0.79 | CYP1A2 (0.57) | ALOX15POLBMAPK1ALDH1A1MAOB | |
| SCHEMBL2992355 | 0.79 | MAOB (0.49) | ALOX15POLBMAPK1ALDH1A1MAOB | |
| SCHEMBL23293634 | 0.79 | ALOX15 (0.48) | ALOX15POLBMAPK1ALDH1A1MAOB | |
| SCHEMBL30074608 | 0.79 | ALOX15 (0.48) | ALOX15POLBMAPK1ALDH1A1MAOB | |
| SCHEMBL4314837 | 0.78 | NPC1 (0.41) | ALDH1A1NPC1RAB9AKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3816156-A1 | RADIOACTIVE COMPOUND FOR TREATMENT OF MELANOMA AND USE THEREOF | Industry Foundation of Chonnam National University (KR) | 2021-05-05 | — | — | EP | disclosed |