Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23315729 | 0.79 | CTNNB1 (0.69) | CTNNB1RAB9ANPC1HPGDTSHR | |
| SCHEMBL23315695 | 0.76 | CTNNB1 (0.59) | CTNNB1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL15581681 | 0.73 | CTNNB1 (0.67) | CTNNB1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL20079919 | 0.73 | CTNNB1 (0.91) | CTNNB1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL654664 | 0.72 | CTNNB1 (1.00) | CTNNB1NPC1HPGDMAPTLMNA | |
| SCHEMBL14495327 | 0.72 | ATM (0.65) | CTNNB1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL20079920 | 0.70 | PKM (0.72) | CTNNB1HPGDTSHRATMALDH1A1 | |
| SCHEMBL20079916 | 0.68 | CTNNB1 (0.77) | CTNNB1RAB9ANPC1HPGDMAPT | |
| SCHEMBL16795707 | 0.68 | TSHR (0.53) | CTNNB1RAB9ANPC1KMT2AHPGD | |
| SCHEMBL27611333 | 0.67 | HPGD (0.82) | CTNNB1RAB9ANPC1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3311666-B1 | DIKETONES AND HYDROXYKETONES AS CATENIN SIGNALING PATHWAY ACTIVATORS | SAMUMED LLC (US) | 2021-05-05 | — | — | EP | disclosed |