Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8179032 | 0.87 | OPRM1 (0.33) | OPRM1OPRD1OPRK1 | |
| SCHEMBL8250090 | 0.86 | SLC22A1 (0.33) | OPRM1 | |
| SCHEMBL13819910 | 0.78 | — | — | |
| SCHEMBL9975644 | 0.78 | — | — | |
| SCHEMBL13819819 | 0.78 | — | — | |
| SCHEMBL16441204 | 0.77 | DRD4 (0.34) | OPRM1 | |
| SCHEMBL19884842 | 0.77 | DRD4 (0.31) | OPRM1 | |
| SCHEMBL21078253 | 0.76 | TSHR (0.32) | — | |
| SCHEMBL22663697 | 0.75 | USP2 (0.32) | — | |
| SCHEMBL14208013 | 0.75 | OPRM1 (0.31) | OPRM1OPRD1OPRK1S1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3517536-B1 | AMINOTRIAZINE DERIVATIVES USEFUL AS TANK-BINDING KINASE INHIBITOR COMPOUNDS | GILEAD SCIENCES INC (US) | 2021-05-05 | — | — | EP | disclosed |