Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25072300 | 0.82 | — | — | |
| SCHEMBL18800903 | 0.78 | TSHR (0.40) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| SCHEMBL23315960 | 0.76 | OPRM1 (0.31) | — | |
| SCHEMBL23680494 | 0.76 | CRHBP (0.31) | — | |
| SCHEMBL22875807 | 0.74 | OPRM1 (0.33) | TSHRTHRB | |
| SCHEMBL15059086 | 0.74 | TSHR (0.39) | TSHRTHRB | |
| SCHEMBL16411503 | 0.74 | — | — | |
| SCHEMBL24575458 | 0.73 | TSHR (0.40) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Ammonia Solution, Strong SCHEMBL20492546 | 0.72 | TSHR (0.37) | TSHRTHRB | |
| SCHEMBL2351395 | 0.72 | TSHR (0.44) | TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133225-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-07-13 | — | — | WO | disclosed |
| WO-2022006543-A1 | 5-[5-(PIPERIDIN-4-YL)THIENO[3,2-C]PYRAZOL-2-YL]INDAZOLE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS FOR SPLICING NUCLEIC ACIDS AND FOR THE TREATMENT OF PROLIFERATIVE DISEASES | REMIX THERAPEUTICS INC. (US) | 2022-01-06 | — | — | WO | disclosed |
| EP-3041841-B1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2019-06-05 | — | — | EP | disclosed |