Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 6/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25151086 | 0.74 | IRAK4 (0.36) | FFAR1IRAK4LPLLIPGF11 | |
| SCHEMBL15176276 | 0.74 | IRAK4 (0.41) | FFAR1IRAK4LPLLIPGF11 | |
| SCHEMBL2959083 | 0.74 | FFAR1 (0.40) | FFAR1IRAK4LPLLIPGDGAT1 | |
| SCHEMBL15175675 | 0.72 | LPL (0.36) | FFAR1IRAK4LPLLIPG | |
| SCHEMBL25295739 | 0.72 | IRAK4 (0.35) | FFAR1IRAK4LPLLIPG | |
| SCHEMBL24718096 | 0.70 | L3MBTL1 (0.50) | FFAR1IRAK4LPLLIPGF11 | |
| SCHEMBL42112 | 0.69 | LPL (0.47) | IRAK4LPLLIPGDGAT1 | |
| SCHEMBL25150881 | 0.69 | IRAK4 (0.33) | FFAR1IRAK4LPLLIPG | |
| SCHEMBL25202785 | 0.69 | FFAR1 (0.34) | FFAR1IRAK4LPLLIPGPDGFRB | |
| SCHEMBL15176393 | 0.69 | FFAR1 (0.36) | FFAR1IRAK4LPLLIPGF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220287748-A1 | PROPHYLACTIC OR THERAPEUTIC AGENT FOR SPINAL MUSCULAR ATROPHY | REBORNA BIOSCIENCES, INC. (JP) | 2022-09-15 | — | — | US | disclosed |
| EP-3816160-A1 | PROPHYLACTIC OR THERAPEUTIC AGENT FOR SPINAL MUSCULAR ATROPHY | Reborna Biosciences, Inc. (JP) | 2021-05-05 | — | — | EP | disclosed |