Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | NMT2 | O60551 | 2/20 | 0.34 |
| ▸ | NMT1 | P30419 | 2/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 2/20 | 0.32 |
| ▸ | RRM1 | P23921 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.32 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14004700 | 0.84 | SIRT6 (0.42) | SIRT6SIRT1NMT2NMT1CACNA1B | |
| SCHEMBL16263587 | 0.76 | SIRT6 (0.42) | SIRT6SIRT1NMT2NMT1CACNA1B | |
| SCHEMBL14002759 | 0.75 | KISS1R (0.43) | SIRT6SIRT1CACNA1BDPP7TLR2 | |
| SCHEMBL14002740 | 0.75 | KISS1R (0.43) | SIRT6SIRT1CACNA1BDPP7TLR2 | |
| SCHEMBL14002552 | 0.74 | KISS1R (0.40) | SIRT6SIRT1NMT2NMT1CACNA1B | |
| SCHEMBL13997045 | 0.73 | KISS1R (0.44) | SIRT6SIRT1NMT2NMT1CACNA1B | |
| SCHEMBL14004873 | 0.73 | SIRT6 (0.40) | SIRT6SIRT1NMT2NMT1CACNA1B | |
| SCHEMBL14004844 | 0.73 | SIRT6 (0.39) | SIRT6SIRT1NMT2NMT1CACNA1B | |
| SCHEMBL14004909 | 0.73 | SIRT6 (0.42) | SIRT6SIRT1NMT2NMT1CACNA1B | |
| SCHEMBL17232578 | 0.72 | FURIN (0.39) | SIRT6SIRT1NMT2NMT1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3426673-B1 | PEPTOID AFFINITY LIGANDS | MIKE ANN LLC (US) | 2021-05-05 | — | — | EP | disclosed |