Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALB | P02768 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.33 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.33 |
| ▸ | POLG | P54098 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12015129 | 0.87 | POLB (0.49) | POLBCACNA1FLMNAALBMAPT | |
| SCHEMBL14512782 | 0.87 | POLB (0.49) | POLBCACNA1FLMNAALBMAPT | |
| SCHEMBL68614 | 0.87 | POLB (0.49) | POLBCACNA1FLMNAALBMAPT | |
| SCHEMBL12885704 | 0.81 | POLB (0.38) | POLBCACNA1FLMNAALBMAPT | |
| SCHEMBL26268704 | 0.79 | DUT (0.47) | RNASE1P2RY2P2RY4P2RY6 | |
| SCHEMBL12015134 | 0.79 | DUT (0.47) | RNASE1P2RY2P2RY4P2RY6 | |
| SCHEMBL12087561 | 0.79 | DUT (0.47) | RNASE1P2RY2P2RY4P2RY6 | |
| SCHEMBL67563 | 0.79 | ALB (0.38) | ALBADRB1DNMT1RNASE1POLG | |
| SCHEMBL12087580 | 0.79 | ALB (0.38) | ALBADRB1DNMT1RNASE1POLG | |
| SCHEMBL12015121 | 0.79 | ALB (0.38) | ALBADRB1DNMT1RNASE1POLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3816286-A1 | MYOCARDIAL DYSFUNCTION THERAPEUTIC AGENT | Daiichi Sankyo Company, Limited (JP) | 2021-05-05 | — | — | EP | disclosed |