Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19046968 | 0.90 | C5AR1 (0.35) | GABRA1FAAHTRPV1GABRG2GABRB3 | |
| SCHEMBL16202644 | 0.80 | HPGD (0.38) | GABRA1FAAHTRPV1GABRG2GABRB3 | |
| SCHEMBL9914264 | 0.79 | FAAH (0.36) | GABRA1FAAHTRPV1GABRG2GABRB3 | |
| SCHEMBL10149300 | 0.77 | FAAH (0.35) | GABRA1FAAHTRPV1GABRG2GABRB3 | |
| SCHEMBL16202642 | 0.76 | HRH3 (0.39) | GABRA1FAAHTRPV1GABRG2GABRB3 | |
| SCHEMBL19964476 | 0.76 | NOTUM (0.54) | HPGDHTR2CHTR2BNOTUMALDH1A1 | |
| SCHEMBL16019534 | 0.74 | TNKS (0.41) | GABRA1FAAHTRPV1GABRG2GABRB3 | |
| SCHEMBL2611041 | 0.73 | NOTUM (0.65) | NOTUM | |
| SCHEMBL19755626 | 0.72 | C5AR1 (0.35) | GABRA1FAAHTRPV1GABRG2GABRB3 | |
| SCHEMBL18373752 | 0.72 | KEAP1 (0.38) | LMNACYP1A2CYP3A4HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265445-B1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA INC (US) | 2021-05-05 | — | — | EP | disclosed |