Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 18/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 17/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23316670 | 0.89 | OPRL1 (0.46) | OPRM1OPRL1 | |
| SCHEMBL23316817 | 0.84 | OPRM1 (0.49) | OPRM1OPRL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23316654 | 0.84 | OPRM1 (0.50) | OPRM1OPRL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20653804 | 0.81 | OPRM1 (0.49) | OPRM1OPRL1 | |
| SCHEMBL23316671 | 0.81 | OPRM1 (0.49) | OPRM1OPRL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19152590 | 0.72 | OPRM1 (0.53) | OPRM1OPRL1 | |
| SCHEMBL23316769 | 0.72 | OPRL1 (0.53) | OPRM1OPRL1 | |
| SCHEMBL23316766 | 0.72 | OPRL1 (0.42) | OPRM1OPRL1 | |
| SCHEMBL20640221 | 0.67 | OPRM1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL20647580 | 0.67 | OPRM1 (1.00) | OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3652157-B1 | 1,3-DIAZA-SPIRO-[3.4]-OCTANE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2021-05-05 | — | — | EP | disclosed |