Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 18/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 17/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23316802 | 0.89 | OPRM1 (0.50) | OPRL1OPRM1 | |
| SCHEMBL23316766 | 0.83 | OPRL1 (0.42) | OPRL1OPRM1OPRK1 | |
| SCHEMBL21766728 | 0.76 | OPRL1 (0.52) | OPRL1OPRM1OPRK1 | |
| SCHEMBL22540261 | 0.73 | OPRM1 (0.46) | OPRL1OPRM1 | |
| SCHEMBL22540385 | 0.72 | OPRL1 (0.48) | OPRL1OPRM1OPRK1 | |
| SCHEMBL19153839 | 0.72 | OPRM1 (0.49) | OPRL1OPRM1 | |
| SCHEMBL21766651 | 0.72 | OPRL1 (0.49) | OPRL1OPRM1OPRK1 | |
| SCHEMBL23316654 | 0.71 | OPRM1 (0.50) | OPRL1OPRM1 | |
| SCHEMBL23316817 | 0.71 | OPRM1 (0.49) | OPRL1OPRM1 | |
| SCHEMBL19153406 | 0.70 | OPRM1 (0.53) | OPRL1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3652157-B1 | 1,3-DIAZA-SPIRO-[3.4]-OCTANE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2021-05-05 | — | — | EP | disclosed |