SCHEMBL2331715

SCHEMBL2331715

CO[Si](CCCCCCCCCCCC#N)(OC)OC

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
LMNA P02545 1/20 0.38
ALDH1A1 P00352 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
MAPT P10636 1/20 0.30
CSNK2A1 P68400 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1802718 1.00 TSHR (0.39) TSHRLMNAALDH1A1TDP1MAPT
SCHEMBL1224251 1.00 TSHR (0.39) TSHRLMNAALDH1A1TDP1MAPT
SCHEMBL3443205 1.00 TSHR (0.39) TSHRLMNAALDH1A1TDP1MAPT
SCHEMBL1224292 0.98 TSHR (0.40) TSHRLMNAALDH1A1TDP1MAPT
SCHEMBL126260 0.91 TSHR (0.42) TSHRLMNAALDH1A1TDP1
SCHEMBL235898 0.80 ALDH1A1 (0.37) TSHRLMNAALDH1A1TDP1
SCHEMBL6009511 0.80 LMNA (0.50) LMNA
SCHEMBL20478196 0.80 LMNA (0.50) LMNA
SCHEMBL20478198 0.80 LMNA (0.50) LMNA
SCHEMBL3741069 0.80 LMNA (0.50) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119725722-A Electrolyte and battery containing same 惠州亿纬锂能股份有限公司 2025-03-28 CN claimed
US-20130095276-A1 MICROPATTERNED SUPERHYDROPHOBIC SILICA BASED SOL-GEL SURFACES DAVE BAKUL C (US) 2013-04-18 US claimed
EP-1546250-B1 ORGANOSILICON COMPOUNDS AND BLENDS FOR TREATING SILICA DOW CORNING (US) 2007-12-19 EP claimed
US-20060292345-A1 Micropatterned superhydrophobic silica based sol-gel surfaces DAVE BAKUL C 2006-12-28 US claimed
EP-1546267-B1 HYDROPHOBING SILICA WITH ORGANOSILICON COMPOUNDS AND BLENDS THEREOF DOW CORNING (US) 2006-05-31 EP claimed
EP-1546267-A2 HYDROPHOBING SILICA WITH ORGANOSILICON COMPOUNDS AND BLENDS THEREOF Dow Corning Corporation (US) 2005-06-29 EP claimed
EP-1546250-A2 ORGANOSILICON COMPOUNDS AND BLENDS FOR TREATING SILICA Dow Corning Corporation (US) 2005-06-29 EP claimed
US-20040227127-A1 Hydrophobing silica with organosilicon compounds and blends thereof BOSWELL LISA MARIE (US) 2004-11-18 US claimed
US-6811823-B2 CONTACTING SILICA SURFACES WITH DIALKYLDICHLOROSILANES AND TRIALKOXYSILANES THAT ARE FREE OF REACTIVE HYDROCARBON OF ORGANOFUNCTIONAL GROUPS; RUBBER TIRES DOW CORNING CORPORATION 2004-11-02 US claimed
EP-0987286-B1 Silicone gels and composites from sheet and tube organofunctional siloxane polymers DOW CORNING (US) 2004-07-14 EP claimed
WO-2004024831-A2 HYDROPHOBING SILICA WITH ORGANOSILICON COMPOUNDS AND BLENDS THEREOF DOW CORNING CORPORATION (US) 2004-03-25 WO claimed
WO-2004024812-A2 ORGANOSILICON COMPOUNDS AND BLENDS FOR TREATING SILICA DOW CORNING CORPORATION (US) 2004-03-25 WO claimed
US-20040052939-A1 Hydrophobing silica with organosilicon compounds and blends thereof DOW CORNING CORPORATION 2004-03-18 US claimed
US-6706398-B1 FORMING HIGHER HYDROPHOBICITY FILLERS; SURFACE TREATMENT WITH COMBINATION OF MONOMERIC DICHLOROSILANES AND TRIALKOXYSILANES DOW CORNING CORPORATION 2004-03-16 US claimed
EP-0987286-A2 Silicone gels and composites from sheet and tube organofunctional siloxane polymers DOW CORNING CORPORATION (US) 2000-03-22 EP claimed
US-6013705-A Silicone gels and composites from sheet and tube organofunctional siloxane polymers DOW CORNING CORPORATION (US) 2000-01-11 US claimed
CN-119725722-A Electrolyte and battery containing same 惠州亿纬锂能股份有限公司 2025-03-28 CN disclosed
EP-4301836-B1 FUNCTIONALIZED MACROPARTICLES OF MESOPOROUS SILICA FOR PROTEIN STABILIZATION AND METAL REMOVAL FROM A BEVERAGE ESSECO S R L (IT) 2025-02-12 EP disclosed
EP-0987286-A2 Silicone gels and composites from sheet and tube organofunctional siloxane polymers DOW CORNING CORPORATION (US) 2000-03-22 EP disclosed
US-6013705-A Silicone gels and composites from sheet and tube organofunctional siloxane polymers DOW CORNING CORPORATION (US) 2000-01-11 US disclosed