Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4091111 | 0.83 | HRH3 (0.49) | CHRM2KMT2AHPGDMEN1ALDH1A1 | |
| SCHEMBL4085362 | 0.83 | HRH3 (0.49) | CHRM2KMT2AHPGDMEN1ALDH1A1 | |
| SCHEMBL11626430 | 0.80 | HRH3 (0.55) | KMT2AMEN1HRH3TSHRHSD17B10 | |
| SCHEMBL12465662 | 0.79 | CHRM2 (0.51) | CHRM2KMT2AHPGDMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6661667 | 0.78 | CHRM2 (0.50) | CHRM2KMT2AHPGDMEN1ALDH1A1 | |
| SCHEMBL4250620 | 0.78 | CHRM2 (0.50) | CHRM2KMT2AHPGDMEN1ALDH1A1 | |
| SCHEMBL6050109 | 0.78 | CHRM2 (0.50) | CHRM2KMT2AHPGDMEN1ALDH1A1 | |
| SCHEMBL4093576 | 0.77 | HRH3 (0.53) | CHRM2KMT2AHPGDMEN1ALDH1A1 | |
| SCHEMBL4079775 | 0.77 | ALDH1A1 (0.52) | CHRM2KMT2AHPGDMEN1ALDH1A1 | |
| SCHEMBL6360979 | 0.77 | HRH3 (0.63) | HRH3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021087113-A1 | LOCAL ANESTHETICS WITH SELECTIVE-SENSORY NERVE BLOCKADE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2021-05-06 | — | — | WO | disclosed |