Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 7/20 | 0.43 |
| ▸ | BPTF | Q12830 | 6/20 | 0.43 |
| ▸ | BRD9 | Q9H8M2 | 5/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.37 |
| ▸ | BRD1 | O95696 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.35 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4292263 | 0.78 | NPC1 (0.50) | KAT2BBPTFBRD9MTORTRPC5 | |
| SCHEMBL2964987 | 0.78 | KAT2B (0.41) | KAT2BBPTFBRD9MTORALDH1A1 | |
| SCHEMBL31735389 | 0.77 | BRD9 (0.42) | KAT2BBPTFBRD9BRPF1BRD7 | |
| SCHEMBL17912381 | 0.75 | KAT2B (0.47) | KAT2BBPTFBRD9MTORTRPC5 | |
| SCHEMBL8281635 | 0.75 | MTOR (0.43) | KAT2BBPTFBRD9MTORTRPC5 | |
| SCHEMBL7010722 | 0.75 | KAT2B (0.56) | KAT2BBPTFBRD9KAT2ABRD7 | |
| SCHEMBL11274814 | 0.75 | PLA2G1B (0.38) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL4498149 | 0.72 | RAB9A (0.55) | KAT2BBPTFBRD9MTORTRPC5 | |
| SCHEMBL10769084 | 0.70 | RAB9A (0.71) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL27557716 | 0.68 | BRD9 (0.34) | KAT2BBPTFBRD9BRPF1KAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021087096-A1 | P53 MODULATORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-05-06 | — | — | WO | disclosed |