Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 2/20 | 0.50 |
| ▸ | XBP1 | P17861 | 2/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 6/20 | 0.42 |
| ▸ | BRD9 | Q9H8M2 | 5/20 | 0.42 |
| ▸ | BPTF | Q12830 | 2/20 | 0.42 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545709 | 0.80 | BRD9 (0.42) | NPC1ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8281635 | 0.78 | MTOR (0.43) | NPC1ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL17912381 | 0.78 | KAT2B (0.47) | ALDH1A1MAPTRAB9ANPSR1MTOR | |
| SCHEMBL17912364 | 0.78 | KAT2B (0.56) | ALDH1A1MAPTRAB9ANPSR1GAA | |
| SCHEMBL13620238 | 0.77 | RAB9A (0.55) | NPC1ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL14844575 | 0.77 | NPBWR1 (0.43) | NPC1ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8549796 | 0.75 | MTOR (0.38) | NPC1ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL4498149 | 0.75 | RAB9A (0.55) | NPC1ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8544525 | 0.74 | SMN1; SMN2 (0.40) | NPC1ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9233774 | 0.72 | SMN1; SMN2 (0.50) | NPC1ALDH1A1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025245484-A1 | FOXN1 ACTIVATORS | THYMOFOX INC. (US) | 2025-11-27 | — | — | WO | disclosed |
| EP-4581025-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | Auron Therapeutics, Inc. (US) | 2025-07-09 | — | — | EP | disclosed |
| WO-2025076219-A1 | METHODS AND COMPOUNDS FOR MODULATING HUNTINGTON'S DISEASE | Design Therapeutics, Inc. (US) | 2025-04-10 | — | — | WO | disclosed |
| WO-2025076236-A1 | METHODS AND COMPOUNDS FOR MODULATING HUNTINGTON'S DISEASE | Design Therapeutics, Inc. (US) | 2025-04-10 | — | — | WO | disclosed |
| WO-2025076181-A1 | METHODS AND COMPOUNDS FOR MODULATING HUNTINGTON'S DISEASE | Design Therapeutics, Inc. (US) | 2025-04-10 | — | — | WO | disclosed |
| WO-2024220843-A1 | TECHNOLOGIES TARGETING CELL STATES | AURON THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |
| WO-2024132895-A1 | MICROBIOCIDAL DIHYDROOXADIAZINYL PYRIDAZINONE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024050078-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | AURON THERAPEUTICS, INC. (US) | 2024-03-07 | — | — | WO | disclosed |
| US-20230391730-A1 | INHIBITORS OF THE BROMODOMAIN PHD FINGER TRANSCRIPTION FACTOR (BPTF) AS ANTI-CANCER AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2023-12-07 | — | — | US | disclosed |
| WO-2023166067-A1 | MICROBIOCIDAL PYRIDAZINONE AMIDE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-09-07 | — | — | WO | disclosed |
| US-5763439-A | POTENTIATION | ISHIHARA SANGYO KAISHA LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| US-5723411-A | Herbicidal pyridazinones | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-03-03 | — | — | US | disclosed |
| EP-0717734-A1 | PYRIDAZINONE DERIVATIVES OR THEIR SALTS, PROCESSES FOR THEIR PRODUCTION, AND ANTI-SHOCK AGENTS CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |
| WO-1995007264-A1 | PYRIDAZINONE DERIVATIVES OR THEIR SALTS, PROCESSES FOR THEIR PRODUCTION, AND ANTI-SHOCK AGENTS CONTAINING THEM | ISHIHARA SANGYO KAISHA LTD. (JP) | 1995-03-16 | — | — | WO | disclosed |
| EP-0372305-B1 | PIPERAZINYLALKYL-3(2H)-PYRIDAZINONES, METHOD FOR THEIR PREPARATION AND THEIR USE AS ANTIHYPERTENSIVE AGENTS | Hafslund Nycomed Pharma Aktiengesellschaft (AT) | 1993-08-04 | — | — | EP | disclosed |
| US-5034391-A | Piperazinylalkyl-3(2H)-pyridazinones and the use thereof as agents lowering blood pressure | CL PHARMA AKTIENGESELLSCHAFT (AT) | 1991-07-23 | — | — | US | disclosed |
| EP-0372305-A1 | Piperazinylalkyl-3(2H)-pyridazinones, method for their preparation and their use as antihypertensive agents | Hafslund Nycomed Pharma Aktiengesellschaft (AT) | 1990-06-13 | — | — | EP | disclosed |
| EP-0135076-B1 | PYRIDAZINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BASF Aktiengesellschaft (DE) | 1987-07-29 | — | — | EP | disclosed |
| US-4663324-A | PRETREATMENT | BASF AKTIENGESELLSCHAFT (DE) | 1987-05-05 | — | — | US | disclosed |
| EP-0135076-A2 | Pyridazinone derivatives, process for their preparation and their use as fungicides | BASF Aktiengesellschaft (DE) | 1985-03-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230391730-A1 | INHIBITORS OF THE BROMODOMAIN PHD FINGER TRANSCRIPTION FACTOR (BPTF) AS ANTI-CANCER AGENTS | BPTF, BRPF3, PHF6 | NPC1 2634/4885ALDH1A1 2997/4885MAPT 3586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.