Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 2/20 | 0.41 |
| ▸ | FNTB | P49356 | 2/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18485876 | 1.00 | LMNA (0.46) | LMNALTA4HALDH1A1NPSR1FOLH1 | |
| SCHEMBL18485872 | 1.00 | LMNA (0.46) | LMNALTA4HALDH1A1NPSR1FOLH1 | |
| SCHEMBL18485873 | 1.00 | LMNA (0.46) | LMNALTA4HALDH1A1NPSR1FOLH1 | |
| SCHEMBL18485882 | 1.00 | LMNA (0.46) | LMNALTA4HALDH1A1NPSR1FOLH1 | |
| SCHEMBL18485886 | 1.00 | LMNA (0.46) | LMNALTA4HALDH1A1NPSR1FOLH1 | |
| SCHEMBL18764132 | 0.85 | ALDH1A1 (0.47) | ALDH1A1USP2 | |
| SCHEMBL18764106 | 0.85 | ALDH1A1 (0.47) | ALDH1A1USP2 | |
| SCHEMBL18764109 | 0.85 | ALDH1A1 (0.47) | ALDH1A1USP2 | |
| SCHEMBL18782968 | 0.84 | LMNA (0.50) | LMNALTA4HALDH1A1NPSR1FOLH1 | |
| SCHEMBL18782970 | 0.84 | LMNA (0.50) | LMNALTA4HALDH1A1NPSR1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3129014-B1 | NOVEL ORGANOSELENIUM COMPOUNDS, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL USES THEREOF AS ANTITUMOUR AGENTS | TETRAHEDRON (FR) | 2021-05-12 | — | — | EP | claimed |