SCHEMBL23319637

SCHEMBL23319637

CCCCc1ccc(-c2cc(-c3ccc(CCCC)cc3)cc(-c3ccc(CCCC)cc3)c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 6/20 0.60
HSD17B10 Q99714 3/20 0.53
TSHR P16473 1/20 0.53
AKR1C2 P52895 1/20 0.53
AKR1C1 Q04828 1/20 0.53
CA2 P00918 2/20 0.52
CA1 P00915 1/20 0.52
ALDH1A1 P00352 3/20 0.52
MEN1 O00255 1/20 0.52
RARA P10276 1/20 0.52
MAPT P10636 1/20 0.52
MTOR P42345 1/20 0.52
KMT2A Q03164 1/20 0.52
HSD11B1 P28845 1/20 0.50
HPGD P15428 1/20 0.50
GPR84 Q9NQS5 1/20 0.49
NISCH Q9Y2I1 1/20 0.49
HRH3 Q9Y5N1 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.48
SKP2 Q13309 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28829434 0.93 RARB (0.67) RARBHSD17B10TSHRCA2CA1
SCHEMBL5551587 0.93 RARB (0.67) RARBHSD17B10TSHRCA2CA1
SCHEMBL28900119 0.90 RARB (0.64) RARBHSD17B10TSHRCA2CA1
SCHEMBL13809302 0.90 RARB (0.51) RARBHSD17B10TSHRAKR1C2AKR1C1
SCHEMBL25951362 0.88 RARB (0.50) RARBHSD17B10TSHRAKR1C2AKR1C1
SCHEMBL18419652 0.86 RARB (0.50) RARBHSD17B10TSHRAKR1C2AKR1C1
SCHEMBL7513802 0.86 RARB (0.60) RARBHSD17B10TSHRCA2CA1
SCHEMBL10379965 0.85 RARB (0.68) RARBHSD17B10TSHRALDH1A1MEN1
SCHEMBL31549867 0.85 RARB (0.68) RARBHSD17B10TSHRALDH1A1MEN1
SCHEMBL83869 0.84 CA2 (0.65) RARBHSD17B10CA2CA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113200812-B 1,3,5-trisubstituted aryl compound synthesis method 天津大学 2023-04-07 CN disclosed
EP-3436552-B1 USE OF TRIARYLBENZENE DERIVATIVES AS TRACERS FOR MARKING LIQUID FUELS AND MOTOR FUELS, LIQUID FUELS AND MOTOR FUELS CONTAINING SUCH DERIVATIVES AND CORRESPONDING PROCESSES ETABLISSEMENTS STEINER (FR) 2021-05-12 EP disclosed