Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | RARA | P10276 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11562537 | 0.93 | RARB (0.61) | RARBHSD17B10TSHRALDH1A1MEN1 | |
| SCHEMBL329514 | 0.93 | CA2 (0.58) | RARBHSD17B10CA2CA1ALDH1A1 | |
| SCHEMBL28829434 | 0.93 | RARB (0.67) | RARBHSD17B10TSHRCA2CA1 | |
| SCHEMBL5551587 | 0.93 | RARB (0.67) | RARBHSD17B10TSHRCA2CA1 | |
| SCHEMBL28900119 | 0.90 | RARB (0.64) | RARBHSD17B10TSHRCA2CA1 | |
| SCHEMBL23319637 | 0.86 | RARB (0.60) | RARBHSD17B10TSHRCA2CA1 | |
| SCHEMBL31549867 | 0.85 | RARB (0.68) | RARBHSD17B10TSHRALDH1A1MEN1 | |
| SCHEMBL1372465 | 0.85 | ESR1 (0.64) | RARBHSD17B10CA2ALDH1A1TAAR1 | |
| SCHEMBL10379965 | 0.85 | RARB (0.68) | RARBHSD17B10TSHRALDH1A1MEN1 | |
| SCHEMBL11566894 | 0.85 | TAAR1 (0.54) | RARBHSD17B10TSHRCA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4180475-A | POSITIVE ANISOTROPY OF DIELECTRIC CONSTANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-12-25 | — | — | US | claimed |
| EP-0742275-B1 | LIQUID CRYSTAL COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORP (JP) | 2002-03-20 | — | — | EP | disclosed |
| EP-0640578-B2 | Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition | CHISSO CORP (JP) | 2001-06-27 | — | — | EP | disclosed |
| EP-0805134-B1 | NOVEL LIQUID-CRYSTAL COMPOUNDS BEARING DIENYL MOIETY AND LIQUID-CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2000-08-30 | — | — | EP | disclosed |
| EP-0733692-B1 | Liquid crystalline compound, liquid crystal composition containing the same, and display device | CHISSO CORP (JP) | 2000-06-14 | — | — | EP | disclosed |
| EP-0727473-B1 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 2000-01-12 | — | — | EP | disclosed |
| EP-0679707-B1 | Liquid crystalline compound, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5779936-A | FLUORINATED BICYCLOHEXANE OR CYCLOHEXYLETHYL CYCLOHEXANE DERIVATIVE HAVING LOW VISCOSITY AND HIGH CLEARING POINT TEMPERATURE | CHISSO CORPORATION (JP) | 1998-07-14 | — | — | US | disclosed |
| US-5720899-A | Liquid crystalline compound, liquid crystal composition and liquid crystal display element | CHISSO CORPORATION (JP) | 1998-02-24 | — | — | US | disclosed |
| EP-0805134-A1 | NOVEL LIQUID-CRYSTAL COMPOUNDS BEARING DIENYL MOIETY AND LIQUID-CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-11-05 | — | — | EP | disclosed |
| EP-0640578-B1 | Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition | CHISSO CORP (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5653911-A | Liquid crystalline compound liquid crystal composition and liquid crystal display element | CHISSO CORPORATION (JP) | 1997-08-05 | — | — | US | disclosed |
| EP-0742275-A1 | LIQUID CRYSTAL COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1996-11-13 | — | — | EP | disclosed |
| EP-0733692-A1 | Liquid crystalline compound, liquid crystal composition containing the same, and display device | Chisso Corporation (JP) | 1996-09-25 | — | — | EP | disclosed |
| EP-0727473-A2 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | Chisso Corporation (JP) | 1996-08-21 | — | — | EP | disclosed |
| EP-0679707-A1 | Liquid crystalline compound, liquid crystal composition and liquid crystal display element | Chisso Corporation (JP) | 1995-11-02 | — | — | EP | disclosed |
| EP-0640578-A1 | Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition | Chisso Corporation (JP) | 1995-03-01 | — | — | EP | disclosed |
| US-4385002-A | REACTING THALLIUM III PERCHLORATE, A CARBOXYLIC ACID, PERCHLORIC ACID AND AN AROMATIC COMPOUND | RUTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1983-05-24 | — | — | US | disclosed |
| US-4180475-A | POSITIVE ANISOTROPY OF DIELECTRIC CONSTANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-12-25 | — | — | US | disclosed |