Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SHMT1 | P34896 | 4/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SHMT2 | P34897 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2335604 | 0.80 | GABRA5 (0.40) | GABRA5GABRB2HSD17B10ALDH1A1MEN1 | |
| SCHEMBL7831829 | 0.75 | GABRA5 (0.59) | GABRA5GABRB2HSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL7380564 | 0.73 | GABRA5 (0.64) | GABRA5GABRB2HSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL909845 | 0.73 | HSD17B10 (1.00) | GABRA5GABRB2HSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL2235871 | 0.72 | GABRA5 (0.51) | GABRA5GABRB2HSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL2235857 | 0.72 | GABRA5 (0.51) | GABRA5GABRB2HSD17B10SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL7998411 | 0.72 | GABRA5 (0.62) | GABRA5GABRB2HSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL28100058 | 0.72 | GABRA5 (0.71) | GABRA5GABRB2HSD17B10POLBSMN1; SMN2 | |
| SCHEMBL7845357 | 0.72 | GABRA5 (0.71) | GABRA5GABRB2HSD17B10POLBSMN1; SMN2 | |
| SCHEMBL1769583 | 0.72 | GABRA5 (0.54) | GABRA5GABRB2HSD17B10SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011095218-A1 | TEMPLATE-FIXED PEP TIDOMIME TICS WITH CXCR7 MODULATING ACTIVITY | POLYPHOR AG (CH) | 2011-08-11 | — | — | WO | disclosed |