Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2331983 | 0.80 | GABRA5 (0.55) | GABRA5GABRB2HSD17B10MEN1ALDH1A1 | |
| SCHEMBL1768610 | 0.78 | LMNA (0.57) | GABRA5GABRB2HSD17B10MEN1NPC1 | |
| SCHEMBL2364022 | 0.77 | KDM4E (0.41) | HDAC1HDAC8HDAC6LMNAHDAC3 | |
| SCHEMBL2364113 | 0.75 | LONP1 (0.46) | KMT2AHPGDHTTLMNA | |
| SCHEMBL19914329 | 0.72 | NPC1 (0.51) | GABRA5GABRB2HSD17B10MEN1NPC1 | |
| SCHEMBL2364158 | 0.72 | HSPA9 (0.42) | ALDH1A1HDAC1HDAC3 | |
| SCHEMBL2364398 | 0.71 | HPGD (0.54) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL2234055 | 0.71 | OTC (0.45) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL2364467 | 0.71 | P2RX7 (0.54) | ALDH1A1HPGDLMNA | |
| SCHEMBL2234043 | 0.71 | OTC (0.45) | MEN1NPC1ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011095218-A1 | TEMPLATE-FIXED PEP TIDOMIME TICS WITH CXCR7 MODULATING ACTIVITY | POLYPHOR AG (CH) | 2011-08-11 | — | — | WO | disclosed |