Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20698952 | 0.89 | NLRP3 (0.35) | NLRP3 | |
| SCHEMBL20681231 | 0.89 | NLRP3 (0.35) | NLRP3F11 | |
| SCHEMBL30791038 | 0.89 | NLRP3 (0.35) | NLRP3F11 | |
| SCHEMBL23692244 | 0.88 | NLRP3 (0.35) | NLRP3 | |
| SCHEMBL24116492 | 0.84 | NLRP3 (0.36) | NLRP3 | |
| SCHEMBL25139038 | 0.84 | NLRP3 (0.34) | NLRP3 | |
| SCHEMBL23319851 | 0.83 | NLRP3 (0.36) | NLRP3 | |
| SCHEMBL21962095 | 0.81 | NLRP3 (0.47) | NLRP3 | |
| SCHEMBL25139101 | 0.81 | NLRP3 (0.30) | NLRP3 | |
| SCHEMBL23319872 | 0.78 | NLRP3 (0.35) | NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210395241-A1 | NLRP MODULATORS | NOVARTIS INFLAMMASOME RESEARCH, INC. | 2021-12-23 | — | — | US | disclosed |
| CN-113613721-A | NLRP modulators | 诺华股份有限公司 | 2021-11-05 | — | — | CN | disclosed |
| EP-3817815-A1 | NLRP MODULATORS | Novartis AG (CH) | 2021-05-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210395241-A1 | NLRP MODULATORS | NLRP1, NLRP3, NOD1 | NLRP3 2/4885F11 4247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.