Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.37 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26089010 | 0.92 | UCHL1 (0.50) | UCHL1SMN1; SMN2POLBRXFP1ALOX15 | |
| SCHEMBL26469523 | 0.89 | UCHL1 (0.48) | UCHL1SMN1; SMN2POLBRXFP1ALOX15 | |
| SCHEMBL24155056 | 0.89 | UCHL1 (0.48) | UCHL1POLBRXFP1ALOX15L3MBTL1 | |
| SCHEMBL22817242 | 0.85 | UCHL1 (0.51) | UCHL1CYP19A1SMN1; SMN2POLBRXFP1 | |
| SCHEMBL22795533 | 0.83 | CYP19A1 (0.57) | UCHL1CYP19A1SMN1; SMN2POLBRXFP1 | |
| SCHEMBL21296893 | 0.83 | CYP19A1 (0.56) | UCHL1CYP19A1SMN1; SMN2POLBRXFP1 | |
| SCHEMBL26467707 | 0.83 | UCHL1 (0.42) | UCHL1CYP19A1POLBALOX15L3MBTL1 | |
| SCHEMBL21296900 | 0.83 | CYP19A1 (0.57) | UCHL1CYP19A1SMN1; SMN2POLBRXFP1 | |
| SCHEMBL23028492 | 0.82 | CYP19A1 (0.46) | UCHL1CYP19A1SMN1; SMN2POLBRXFP1 | |
| SCHEMBL22795504 | 0.82 | POLB (0.48) | UCHL1CYP19A1SMN1; SMN2POLBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3817816-A1 | TRIAZOLE GLYCOLATE OXIDASE INHIBITORS | Orfan Biotech Inc. (US) | 2021-05-12 | — | — | EP | disclosed |
| CN-112399873-A | Triazole glycolate oxidase inhibitor | 奥凡生物科技公司 | 2021-02-23 | — | — | CN | disclosed |