SCHEMBL26467707

SCHEMBL26467707

CC(=O)c1nnn(Cc2ccc(C)cc2)c1Oc1ccc(B2OC(C)(C)C(C)(C)O2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UCHL1 P09936 1/20 0.42
HIF1A Q16665 1/20 0.39
CYP19A1 P11511 1/20 0.37
POLB P06746 2/20 0.36
TSHR P16473 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
LPL P06858 1/20 0.35
LIPG Q9Y5X9 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
F11 P03951 2/20 0.35
ALOX15 P16050 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
F2 P00734 1/20 0.35
PRSS1 P07477 1/20 0.35
PRSS2 P07478 1/20 0.35
PRSS3 P35030 1/20 0.35
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26467692 0.86 CYP19A1 (0.46) CYP19A1POLBTSHRMEN1KMT2A
SCHEMBL24155056 0.84 UCHL1 (0.48) UCHL1POLBMEN1KMT2AF11
SCHEMBL26089010 0.83 UCHL1 (0.50) UCHL1HIF1APOLBMEN1KMT2A
SCHEMBL23319940 0.83 UCHL1 (0.59) UCHL1CYP19A1POLBMEN1KMT2A
SCHEMBL26469523 0.81 UCHL1 (0.48) UCHL1POLBMEN1KMT2AALOX15
SCHEMBL26467679 0.81 CYP19A1 (0.45) CYP19A1POLBTSHRMEN1KMT2A
SCHEMBL26467681 0.74 CYP19A1 (0.39) CYP19A1POLBTSHRMEN1KMT2A
SCHEMBL26467846 0.73 ALOX15 (0.49) CYP19A1POLBMEN1KMT2AALOX15
SCHEMBL26467790 0.71 SMN1; SMN2 (0.47) CYP19A1POLBTSHRMEN1KMT2A
SCHEMBL623833 0.70 CA1 (0.54) HIF1APOLBLPLLIPGCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230129160-A1 PROCESSES FOR PREPARING TRIAZOLE GLYCOLATE OXIDASE INHIBITORS PHOENIX TISSUE REPAIR, INC. 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230129160-A1 PROCESSES FOR PREPARING TRIAZOLE GLYCOLATE OXIDASE INHIBITORS TH, AOX1, AOC3 UCHL1 441/4885HIF1A 1412/4885CYP19A1 247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.