SCHEMBL23319986

SCHEMBL23319986

Cc1ccc(Oc2[nH]nnc2C(=O)O)cn1

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HAO1 Q9UJM8 11/20 0.52
P2RY14 Q15391 5/20 0.39
KMT2A Q03164 2/20 0.38
MAPT P10636 1/20 0.36
GRM5 P41594 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23319935 0.90 HAO1 (0.48) HAO1KMT2A
SCHEMBL25465031 0.86 HAO1 (0.45) HAO1P2RY14KMT2AMAPTGRM5
SCHEMBL29692495 0.86 HAO1 (0.69) HAO1
SCHEMBL23001884 0.86 HAO1 (0.69) HAO1
SCHEMBL23319889 0.84 HAO1 (0.54) HAO1KMT2AMAPT
SCHEMBL23319929 0.83 NAPRT (0.41) HAO1
SCHEMBL21312442 0.82 GAA (0.45) HAO1KMT2A
SCHEMBL23001974 0.81 HAO1 (0.47) HAO1
SCHEMBL29964033 0.81 HAO1 (0.47) HAO1
SCHEMBL23319961 0.80 HAO1 (0.39) HAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230143491-A1 TRIAZOLE GLYCOLATE OXIDASE INHIBITORS PHOENIX TISSUE REPAIR, INC. 2023-05-11 US disclosed
US-20230143491-A1 TRIAZOLE GLYCOLATE OXIDASE INHIBITORS PHOENIX TISSUE REPAIR, INC. 2023-05-11 US disclosed
US-20230143491-A1 TRIAZOLE GLYCOLATE OXIDASE INHIBITORS PHOENIX TISSUE REPAIR, INC. 2023-05-11 US disclosed
US-20210403439-A1 TRIAZOLE GLYCOLATE OXIDASE INHIBITORS VENTHERA, INC. 2021-12-30 US disclosed
EP-3817816-A1 TRIAZOLE GLYCOLATE OXIDASE INHIBITORS Orfan Biotech Inc. (US) 2021-05-12 EP disclosed
CN-112399873-A Triazole glycolate oxidase inhibitor 奥凡生物科技公司 2021-02-23 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230143491-A1 TRIAZOLE GLYCOLATE OXIDASE INHIBITORS XDH, DUOX1, PNPO HAO1 6/4885P2RY14 2079/4885KMT2A 3280/4885
US-20210403439-A1 TRIAZOLE GLYCOLATE OXIDASE INHIBITORS XDH, DUOX1, PNPO HAO1 6/4885P2RY14 2079/4885KMT2A 3280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.