SCHEMBL23320216

SCHEMBL23320216

CCc1cccc(CC)c1/N=C1C(=N/c2c(CC)cccc2CC)/C2c3cc4ccccc4cc3C/1c1cc3ccccc3cc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.40
GABRB2 P47870 4/20 0.40
CYP1A2 P05177 1/20 0.34
CYP2A6 P11509 1/20 0.34
DAO P14920 1/20 0.33
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
CSNK2A1 P68400 1/20 0.32
CSNK2A3 Q8NEV1 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
SLC9A1 P19634 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
HTR2B P41595 2/20 0.30
HSP90AA1 P07900 1/20 0.30
PAX8 Q06710 1/20 0.30
HTR7 P34969 1/20 0.30
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23332017 0.87 GABRA1 (0.31) GABRA1GABRB2
SCHEMBL23320264 0.78 POLB (0.37) CYP1A2CYP2A6KDM4EALDH1A1MAPT
SCHEMBL19625543 0.69 CYP1B1 (0.44) GABRA1GABRB2KDM4EALDH1A1MAPT
SCHEMBL2671730 0.66 GABRA1 (0.38) GABRA1GABRB2CYP1A2CYP2A6DAO
SCHEMBL31379941 0.65 ALDH1A1 (0.42) CYP1A2CYP2A6KDM4EALDH1A1MAPT
SCHEMBL31123508 0.65 ALDH1A1 (0.42) CYP1A2CYP2A6KDM4EALDH1A1MAPT
SCHEMBL7542307 0.65 CYP2A6 (0.54) GABRA1GABRB2CYP1A2CYP2A6DAO
SCHEMBL31619719 0.65 CYP1B1 (0.40) GABRA1GABRB2KDM4EALDH1A1MAPT
SCHEMBL31619755 0.64 ALDH1A1 (0.37) GABRA1GABRB2CYP1A2KDM4EALDH1A1
SCHEMBL498622 0.64 ALDH1A1 (0.46) GABRA1GABRB2CYP1A2CYP2A6DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220396646-A1 METHOD FOR PREPARING OLEFIN-POLAR MONOMER COPOLYMER BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2022-12-15 US disclosed
WO-2021083350-A1 DIIMINE METAL COMPLEX, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 中国石油化工股份有限公司 2021-05-06 WO disclosed
WO-2021083358-A1 METHOD FOR PREPARING OLEFIN-POLAR MONOMER COPOLYMER 中国石油化工股份有限公司 2021-05-06 WO disclosed