Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 10/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PRMT3 | O60678 | 2/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30943290 | 0.90 | NAMPT (0.69) | NAMPT | |
| SCHEMBL23320429 | 0.90 | NAMPT (0.69) | NAMPT | |
| SCHEMBL23320516 | 0.83 | NAMPT (0.82) | NAMPTKDM4EPRMT3ROCK2ROCK1 | |
| SCHEMBL23320570 | 0.78 | NAMPT (0.41) | NAMPTKDM4ESMN1; SMN2 | |
| SCHEMBL23320448 | 0.73 | PRMT3 (0.48) | NAMPTKDM4EPRMT3ROCK2ROCK1 | |
| SCHEMBL23320444 | 0.73 | NAMPT (1.00) | NAMPTPRMT3 | |
| SCHEMBL30323627 | 0.72 | CA12 (0.50) | NAMPTKDM4ESMN1; SMN2 | |
| SCHEMBL28632960 | 0.72 | CA12 (0.50) | NAMPTKDM4ESMN1; SMN2 | |
| SCHEMBL23320477 | 0.72 | NAMPT (0.60) | NAMPTKDM4EPRMT3ROCK2ROCK1 | |
| SCHEMBL2056389 | 0.70 | KDM4E (0.72) | NAMPTKDM4EROCK2ROCK1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |