Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | ATM | Q13315 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HK1 | P19367 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10067380 | 0.90 | CYP11B2 (0.68) | ALDH1A1LMNACYP11B2HSD17B10CYP2C19 | |
| Formamide SCHEMBL18162619 | 0.80 | KDM4E (0.50) | ALDH1A1LMNAHSD17B10CYP2C19L3MBTL1 | |
| Formamide SCHEMBL23320513 | 0.79 | MAPT (0.58) | ALDH1A1LMNAL3MBTL1SMN1; SMN2MAPT | |
| Formamide SCHEMBL19211770 | 0.78 | KDM4E (0.49) | ALDH1A1LMNAHSD17B10CYP2C19L3MBTL1 | |
| SCHEMBL1429358 | 0.77 | ALDH1A1 (1.00) | ALDH1A1LMNAHSD17B10CYP2C19L3MBTL1 | |
| SCHEMBL28811227 | 0.77 | CYP11B2 (0.56) | ALDH1A1LMNACYP11B2HSD17B10CYP2C19 | |
| SCHEMBL28593695 | 0.74 | GRIK2 (0.67) | ALDH1A1LMNACYP11B2HSD17B10CYP2C19 | |
| SCHEMBL4785226 | 0.74 | ALDH1A1 (0.57) | ALDH1A1LMNACYP11B2HSD17B10CYP2C19 | |
| SCHEMBL19052340 | 0.73 | MEN1 (0.50) | ALDH1A1LMNACYP11B2HSD17B10CYP2C19 | |
| SCHEMBL1606034 | 0.73 | CYP11B2 (1.00) | ALDH1A1LMNACYP11B2HSD17B10CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654608-B | Fused ring compound having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2024-05-07 | — | — | CN | disclosed |
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |
| CN-112654608-A | Condensed ring compounds having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2021-04-13 | — | — | CN | disclosed |