Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9911978 | 0.77 | PTGS2 (0.40) | ENPP3ENPP1PTGS2TLR7 | |
| SCHEMBL18214769 | 0.74 | ENPP3 (0.32) | ENPP3ENPP1PTGS2 | |
| SCHEMBL16996969 | 0.74 | ENPP3 (0.34) | ENPP3ENPP1PTGS2 | |
| SCHEMBL29131216 | 0.72 | ENPP3 (0.34) | ENPP3ENPP1PTGS2 | |
| SCHEMBL18214835 | 0.71 | ENPP3 (0.32) | ENPP3ENPP1 | |
| SCHEMBL2656541 | 0.70 | ENPP3 (0.42) | ENPP3ENPP1 | |
| SCHEMBL18867386 | 0.67 | ENPP3 (0.35) | ENPP3ENPP1 | |
| SCHEMBL3889765 | 0.65 | CCR1 (0.40) | — | |
| SCHEMBL1127860 | 0.64 | — | — | |
| SCHEMBL17198888 | 0.64 | ENPP3 (0.33) | ENPP3ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818063-A1 | FUSED PYRAZINE DERIVATIVES AS A2A / A2B INHIBITORS | Incyte Corporation (US) | 2021-05-12 | — | — | EP | disclosed |