Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30926398 | 0.81 | CYP2D6 (0.46) | LMNAPMP22NPSR1GFERHSD17B3 | |
| SCHEMBL2510978 | 0.75 | ALDH1A1 (0.40) | CYP2D6ALDH1A1PKM | |
| SCHEMBL2511201 | 0.75 | ALDH1A1 (0.40) | CYP2D6ALDH1A1PKM | |
| SCHEMBL16435121 | 0.73 | CYP11B2 (0.38) | HSD17B3CYP1A2SRD5A1ALDH1A1PKM | |
| SCHEMBL16435103 | 0.73 | HSD17B3 (0.45) | HSD17B3CYP1A2SRD5A1HDAC1HDAC6 | |
| SCHEMBL17419131 | 0.73 | SRD5A1 (0.55) | HSD17B3CYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL31597788 | 0.73 | SRD5A1 (0.55) | HSD17B3CYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL1896345 | 0.71 | CUL4A (0.49) | ALDH1A1SDCBPSDC2 | |
| SCHEMBL16435033 | 0.71 | HSD17B3 (0.45) | HSD17B3CYP1A2 | |
| SCHEMBL3783027 | 0.70 | HSD17B3 (0.40) | LMNAPMP22NPSR1GFERHSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3819305-A1 | AMIDE COMPOUND HAVING BET PROTEOLYSIS-INDUCING ACTION AND MEDICINAL APPLICATION THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2021-05-12 | — | — | EP | disclosed |