⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536275 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL6154472 | 0.69 | — | — | |
| SCHEMBL559604 | 0.67 | TP53 (0.38) | — | |
| SCHEMBL27910344 | 0.67 | TP53 (0.53) | — | |
| SCHEMBL536767 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL28907425 | 0.65 | TP53 (0.39) | — | |
| SCHEMBL537308 | 0.65 | TP53 (0.39) | — | |
| SCHEMBL28215974 | 0.64 | TP53 (0.36) | — | |
| SCHEMBL2818039 | 0.64 | TP53 (0.37) | — | |
| SCHEMBL1680804 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109574960-A | A kind of docetaxel derivative and its preparation method and application | 南京友怡医药科技有限公司 | 2019-04-05 | — | — | CN | claimed |
| CN-108192003-A | A kind of free radical thylene maleic acid anhydride copolymer and its synthetic method | 中山大学 | 2018-06-22 | — | — | CN | claimed |
| US-20250206740-A1 | PIPERIDINYL-METHYLPURINE PYRIMIDINES AND RELATED COMPOUNDS AND THEIR USE IN TREATING DISEASES AND CONDITIONS | K36 THERAPEUTICS, INC. | 2025-06-26 | — | — | US | disclosed |
| WO-2023230038-A1 | PIPERIDINYL-METHYLPURINE PYRIMIDINES AND RELATED COMPOUNDS AND THEIR USE IN TREATING DISEASES AND CONDITIONS | K36 THERAPEUTICS, INC. (US) | 2023-11-30 | — | — | WO | disclosed |
| EP-3131897-B1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME (US) | 2022-06-15 | — | — | EP | disclosed |
| CN-110114349-A | Thiophene derivant as antivirotic | 埃尼奥制药公司 | 2019-08-09 | — | — | CN | disclosed |
| CN-110099907-A | The Thienopyrroles derivative of targeting protein, composition, method and application thereof | 拜欧赛里克斯公司 | 2019-08-06 | — | — | CN | disclosed |
| CN-109906221-A | N- alkyl sulphonyl sulfonylindoline compounds and salt, garderning pesticide and its application method containing the compound | 日本农药株式会社 | 2019-06-18 | — | — | CN | disclosed |
| CN-109030683-B | A method of bipyridyl and 1- methyl chloropyridine content in measurement paraquat waste liquid | 天津市天大赛达协同创新科技研究院有限公司 | 2019-04-05 | — | — | CN | disclosed |
| EP-3131896-B1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME (US) | 2019-01-30 | — | — | EP | disclosed |
| CN-109030683-A | A method of bipyridyl and 1- methyl chloropyridine content in measurement paraquat waste liquid | 天津市天大赛达协同创新科技研究院有限公司 | 2018-12-18 | — | — | CN | disclosed |
| WO-2002030907-A1 | PYRAZOLE DERIVATIVES FOR THE TREATMENT OF VIRAL DISEASES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-04-18 | — | — | WO | disclosed |
| CN-1045434-C | N-oxy-and thioalkylcarbonyloxyaikylpyrrole insecticidal, acaricidal and molluscicidal agents | AMERICAN CYANAMID CO (US) | 1999-10-06 | — | — | CN | disclosed |
| US-5679694-A | LOW TOXICITY AGAINST NORMAL CELL LINES | THE WELLCOME FOUNDATION LTD. (GB) | 1997-10-21 | — | — | US | disclosed |
| EP-0651750-A1 | TETRACYCLIC COMPOUNDS PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOUR AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-05-10 | — | — | EP | disclosed |
| CN-1088209-A | Heterogeneous ring compound | WELLCOME FOUND (GB) | 1994-06-22 | — | — | CN | disclosed |
| WO-1994002483-A1 | TETRACYCLIC COMPOUNDS PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOUR AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-02-03 | — | — | WO | disclosed |
| US-4814489-A | ALKYLATION | MONSANTO COMPANY (US) | 1989-03-21 | — | — | US | disclosed |
| US-RE32154-E | FROM BENZO-THIETANE-2-SPIRO-2'(1,3'-DIZACCYCLOALKANE AND ALKYL HALIDE | BASF AKTIENGESELLSCHAFT (DE) | 1986-05-20 | — | — | US | disclosed |
| US-4122263-A | REACTING A BENZOTHIETANE-2-SPIRO-2'(1',3'-DIAZACYCLOALKANE) WITH AN ALKYL HALIDE | BASF AKTIENGESELLSCHAFT (DE) | 1978-10-24 | — | — | US | disclosed |