SCHEMBL537308

SCHEMBL537308

ClCCCCn1cccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.39
TBXAS1 P24557 1/20 0.32
ALDH1A1 P00352 2/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NPC1 O15118 6/20 0.31
RAB9A P51151 6/20 0.31
HTT P42858 5/20 0.31
LMNA P02545 3/20 0.31
APOBEC3A P31941 2/20 0.31
APOBEC3G Q9HC16 2/20 0.31
PABPC1 P11940 1/20 0.31
GALR3 O60755 2/20 0.30
POLB P06746 2/20 0.30
ATM Q13315 2/20 0.30
MAPK1 P28482 2/20 0.30
NPSR1 Q6W5P4 2/20 0.30
SMN1; SMN2 Q16637 2/20 0.30
KDM4E B2RXH2 1/20 0.30
HSP90AA1 P07900 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2818039 0.97 TP53 (0.37) TP53TBXAS1ALDH1A1TSHRTDP1
SCHEMBL536784 0.97 TP53 (0.37) TP53TBXAS1ALDH1A1TSHRTDP1
SCHEMBL2813982 0.92
Hydrochloric Acid SCHEMBL28907425 0.89 TP53 (0.39) TP53ALDH1A1TSHRTDP1
SCHEMBL20465806 0.85 TP53 (0.48) TP53TBXAS1ALDH1A1TSHRNPC1
SCHEMBL27458343 0.82 TP53 (0.46) TP53TBXAS1ALDH1A1NPC1RAB9A
SCHEMBL536275 0.79
SCHEMBL691481 0.78 TP53 (0.48) TP53TBXAS1ALDH1A1TSHRNPC1
Hydrochloric Acid SCHEMBL6154472 0.77
SCHEMBL536585 0.72 TP53 (0.39) TP53TBXAS1ALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117285512-A 2, 5-diketopiperazine-imidazole compound, preparation method and application thereof 大连万众益生大健康有限公司 2023-12-26 CN disclosed
EP-2414432-B1 AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION CHEVRON ORONITE CO (US) 2017-05-31 EP disclosed
US-9315595-B2 Amine-terminated telechelic polymers and precursors thereto and methods for their preparation CHEVRON ORONITE COMPANY LLC (US) 2016-04-19 US disclosed
CN-102356114-B Amine-terminated telechelic polymers and precursors thereto and methods for their preparation CHEVRON ORONITE CO 2014-06-25 CN disclosed
US-20140031497-A1 AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2014-01-30 US disclosed
US-8552122-B2 Amine-terminated telechelic polymers and precursors thereto and methods for their preparation THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2013-10-08 US disclosed
CN-102356114-A Amine-terminated telechelic polymers and precursors thereto and methods for their preparation CHEVRON ORONITE CO 2012-02-15 CN disclosed
EP-2414432-A2 AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION Chevron Oronite Company LLC (US) 2012-02-08 EP disclosed
WO-2010117619-A2 AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION CHEVRON ORONITE COMPANY LLC (US) 2010-10-14 WO disclosed
US-20100249001-A1 AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION UNIVERSITY OF SOUTHERN MISSISSIPPI 2010-09-30 US disclosed
EP-0507696-B1 Antihistaminic and non-sedative derivatives of benzimidazol, process for their preparation and their medicinal use ESTEVE LABOR DR (ES) 1995-08-09 EP disclosed
CN-1028367-C Benzimidazole derivatives and their preparation ESTEVE LABOR DR (ES) 1995-05-10 CN disclosed
US-5214040-A Side effect reduction LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 1993-05-25 US disclosed
CN-1065460-A Be derived from the new non-sedative antihistamine agent of benzoglyoxaline ESTEVE LABOR DR (ES) 1992-10-21 CN disclosed
EP-0507696-A1 Antihistaminic and non-sedative derivatives of benzimidazol, process for their preparation and their medicinal use LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 1992-10-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249001-A1 AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION TERT, TELO2, TSPO TP53 3927/4885TBXAS1 90/4885ALDH1A1 3744/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.