SCHEMBL536275

SCHEMBL536275

ClCCn1cccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6154472 0.97
SCHEMBL2813982 0.81
Heptane SCHEMBL28868822 0.81 TSHR (0.44)
SCHEMBL537308 0.79 TP53 (0.39)
Hydrochloric Acid SCHEMBL28907425 0.79 TP53 (0.39)
SCHEMBL27910344 0.78 TP53 (0.53)
SCHEMBL536784 0.77 TP53 (0.37)
SCHEMBL2818039 0.77 TP53 (0.37)
SCHEMBL2332259 0.72
SCHEMBL20465806 0.72 TP53 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119711040-A Far infrared fiber thermal fabric and preparation method and application thereof 广东洪兴实业股份有限公司 2025-03-28 CN claimed
CN-105017282-A Pacritinib preparing method SUZHOU MIRACPHARMA TECHNOLOGY CO LTD 2015-11-04 CN claimed
CN-117285470-B Electropolymerizable ionic liquid, polymer, battery pole piece and preparation method thereof TIANMU LAKE INSTITUTE OF ADVANCED ENERGY STORAGE TECHNOLOGIES Co.,Ltd. (CN) 2026-05-26 CN disclosed
CN-119711040-B Far infrared fiber thermal fabric and preparation method and application thereof 广东洪兴实业股份有限公司 2025-06-06 CN disclosed
US-12312348-B2 RET inhibitors, pharmaceutical compositions and uses thereof SUNSHINE LAKE PHARMA CO., LTD. (CN) 2025-05-27 US disclosed
CN-119711040-A Far infrared fiber thermal fabric and preparation method and application thereof 广东洪兴实业股份有限公司 2025-03-28 CN disclosed
CN-119711040-A Far infrared fiber thermal fabric and preparation method and application thereof 广东洪兴实业股份有限公司 2025-03-28 CN disclosed
CN-119192183-A Benzodiazepines class of compounds and uses thereof 中国药科大学 2024-12-27 CN disclosed
CN-111285874-B RET inhibitor, pharmaceutical composition thereof and application thereof 广东东阳光药业股份有限公司 2024-08-09 CN disclosed
CN-117417688-B Salt mist, seepage and carbonization preventing single-component polyurea applied to full-capacity LNG receiving station and preparation method thereof 天津迈特瑞欧科技有限公司 2024-04-19 CN disclosed
CN-117916219-A Quaternary amine salt compound for resisting bladder cancer and application thereof 石家庄迪斯凯威医药科技有限公司 2024-04-19 CN disclosed
EP-1246799-A1 SUBSTITUTED PYRROLE MANNICH BASES TO COMBAT PAIN AND ALLERGIC REACTIONS Grünenthal GmbH (DE) 2002-10-09 EP disclosed
CN-1073559-C Method for preparing chloro-ethyl pyrrolidone UNIV GUANGDONG POLYTECHNICAL (CN) 2001-10-24 CN disclosed
WO-2001047878-A1 SUBSTITUTED PYRROLE MANNICH BASES TO COMBAT PAIN AND ALLERGIC REACTIONS Grünenthal GmbH (DE) 2001-07-05 WO disclosed
WO-2001047882-A2 SUBSTANCE LIBRARY WHICH CAN BE OBTAINED BY REACTING ALDEHYDES WITH SECONDARY AMINES, ACID CHLORIDES AND NAPHTHOL, PYRROLE AND/OR INDOLE COMPOUNDS Grünenthal GmbH (DE) 2001-07-05 WO disclosed
CN-1242361-A Method for preparing chloro-ethyl pyrrolidone UNIV GUANGDONG POLYTECHNICAL (CN) 2000-01-26 CN disclosed
US-RE34201-E Analgesics ANAQUEST, INC. (US) 1993-03-23 US disclosed
US-5053411-A Analgesics ANAQUEST, INC. (US) 1991-10-01 US disclosed
EP-0396282-A2 N-aryl-N-[4-(heterocyclicalkyl) piperidinyl]amides and pharmaceutical compositions and methods employing such compounds BOC, INC. (US) 1990-11-07 EP disclosed
US-3960886-A Substituted N-arylanilines STERLING DRUG INC. (US) 1976-06-01 US disclosed