SCHEMBL2332265

SCHEMBL2332265

CC(C)n1c(=O)n(C(=O)NCC2CCN(CC(COc3ccc(F)cc3)OC(N)=O)CC2)c2ccccc21

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR4 Q13639 7/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15103540 0.94 HTR4 (0.56) HTR4
SCHEMBL15103576 0.93 HTR4 (0.54) HTR4
SCHEMBL15103518 0.92 HTR4 (0.53) HTR4
SCHEMBL2336422 0.91 HTR4 (0.41) HTR4
SCHEMBL2333122 0.89 HTR4 (0.54) HTR4
SCHEMBL2336956 0.88 HTR4 (0.57) HTR4
SCHEMBL2333382 0.86 HTR4 (0.56) HTR4
SCHEMBL3300247 0.85 HTR4 (0.54) HTR4
Hydrochloric Acid SCHEMBL3301028 0.85 HTR4 (0.53) HTR4
SCHEMBL15103575 0.84 HTR4 (0.43) HTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2358702-B1 PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE SK BIOPHARMACEUTICALS CO LTD (KR) 2013-07-17 EP claimed
EP-2358702-A2 PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE SK Holdings Co., Ltd. (KR) 2011-08-24 EP claimed
WO-2010044585-A2 PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE SK HOLDINGS CO., LTD. (KR) 2010-04-22 WO claimed
EP-2358702-B1 PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE SK BIOPHARMACEUTICALS CO LTD (KR) 2013-07-17 EP disclosed