Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15103575 | 0.94 | HTR4 (0.43) | HTR4FAAHACHE | |
| SCHEMBL2337032 | 0.93 | ACHE (0.43) | HTR4CYP2D6FAAHACHEKMT2A | |
| Hydrochloric Acid SCHEMBL2337272 | 0.93 | HTR4 (0.43) | HTR4FAAHACHE | |
| SCHEMBL2333495 | 0.92 | FAAH (0.43) | HTR4TSHRCYP2D6FAAHACHE | |
| SCHEMBL2335214 | 0.91 | HTR4 (0.40) | HTR4FAAHACHEMEN1KMT2A | |
| SCHEMBL2332265 | 0.91 | HTR4 (0.53) | HTR4 | |
| SCHEMBL2331954 | 0.88 | TSHR (0.52) | TSHRCYP2D6MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3304278 | 0.87 | TSHR (0.52) | TSHRCYP2D6 | |
| SCHEMBL3301369 | 0.85 | HTR4 (0.42) | HTR4TSHRCYP2D6FAAHACHE | |
| SCHEMBL15103540 | 0.84 | HTR4 (0.56) | HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358702-B1 | PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE | SK BIOPHARMACEUTICALS CO LTD (KR) | 2013-07-17 | — | — | EP | disclosed |
| EP-2358702-A2 | PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE | SK Holdings Co., Ltd. (KR) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010044585-A2 | PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE | SK HOLDINGS CO., LTD. (KR) | 2010-04-22 | — | — | WO | disclosed |