Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | Q9HBH1 | 1/20 | 0.33 | |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2332493 | 1.00 | LMNA (0.39) | LMNAALDH1A1KMT2APDFCA12 | |
| SCHEMBL11066540 | 0.93 | LMNA (0.35) | LMNAALDH1A1KMT2APDFMEN1 | |
| SCHEMBL1646230 | 0.90 | ALDH1A1 (0.34) | LMNAALDH1A1KMT2ACA12CA14 | |
| SCHEMBL1646228 | 0.90 | ALDH1A1 (0.34) | LMNAALDH1A1KMT2ACA12CA14 | |
| SCHEMBL28126654 | 0.88 | ALDH1A1 (0.47) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10965572 | 0.86 | MEN1 (0.37) | LMNAALDH1A1KMT2APDFMEN1 | |
| SCHEMBL28277872 | 0.83 | TSHR (0.42) | LMNAALDH1A1CA12CA14SMN1; SMN2 | |
| SCHEMBL20241539 | 0.83 | CA12 (0.35) | LMNAALDH1A1KMT2ACA12CA14 | |
| SCHEMBL806095 | 0.82 | TSHR (0.33) | LMNAALDH1A1PDFSMN1; SMN2MAPT | |
| SCHEMBL6775939 | 0.80 | LMNA (0.44) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167494-B1 | 3-AMINO-6-(1-AMINO-ETHYL)-TETRAHYDROPYRAN DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2011-08-17 | — | — | EP | disclosed |