Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17538514 | 0.87 | ELANE (0.41) | ELANEMEN1CYP2C19KMT2ACHRM2 | |
| SCHEMBL15783540 | 0.85 | ELANE (0.40) | ELANEMEN1CYP2C19KMT2ACHRM2 | |
| SCHEMBL18904825 | 0.82 | ELANE (0.37) | ELANEMEN1CYP2C19KMT2ACHRM2 | |
| SCHEMBL21482241 | 0.79 | ELANE (0.37) | ELANEMEN1CYP2C19KMT2ACHRM2 | |
| SCHEMBL20711853 | 0.76 | ELANE (0.34) | ELANEMEN1CYP2C19KMT2ACHRM2 | |
| SCHEMBL17339762 | 0.76 | ALDH1A1 (0.44) | ELANEMEN1CYP2C19KMT2AALDH1A1 | |
| SCHEMBL25807915 | 0.76 | ELANE (0.34) | ELANEMEN1CYP2C19KMT2ACHRM2 | |
| SCHEMBL17251265 | 0.76 | ALDH1A1 (0.39) | ELANEMEN1CYP2C19KMT2AL3MBTL1 | |
| SCHEMBL13245020 | 0.76 | L3MBTL1 (0.45) | ELANEMEN1CYP2C19KMT2AANPEP | |
| SCHEMBL14855193 | 0.76 | L3MBTL1 (0.45) | ELANEMEN1CYP2C19KMT2AANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234929-A1 | RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2023-07-27 | — | — | US | disclosed |
| US-11566007-B2 | Ras inhibitors | Revolution Medicines, Inc. (US) | 2023-01-31 | — | — | US | disclosed |
| US-20210130303-A1 | RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11566007-B2 | Ras inhibitors | KRAS, NRAS, HRAS | ELANE 1926/4885MEN1 815/4885CYP2C19 3930/4885 |
| US-20230234929-A1 | RAS INHIBITORS | KRAS, NRAS, HRAS | ELANE 1926/4885MEN1 815/4885CYP2C19 3930/4885 |
| US-20210130303-A1 | RAS INHIBITORS | KRAS, NRAS, HRAS | ELANE 1926/4885MEN1 815/4885CYP2C19 3930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.