Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 8/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1661430 | 0.88 | HSD17B3 (0.63) | HSD17B3L3MBTL1STSHTR7NPC1 | |
| SCHEMBL5539337 | 0.86 | HSD17B3 (0.65) | HSD17B3L3MBTL1STSHTR7TDP1 | |
| SCHEMBL27625190 | 0.85 | HSD17B3 (0.55) | HSD17B3L3MBTL1HPGDSMN1; SMN2STS | |
| SCHEMBL4611644 | 0.84 | HSD17B3 (0.66) | HSD17B3L3MBTL1STSHTR7TDP1 | |
| SCHEMBL9564629 | 0.84 | HSD17B3 (0.66) | HSD17B3L3MBTL1STSHTR7TDP1 | |
| SCHEMBL9564630 | 0.84 | HSD17B3 (0.66) | HSD17B3L3MBTL1STSHTR7TDP1 | |
| SCHEMBL9564652 | 0.84 | HSD17B3 (0.66) | HSD17B3L3MBTL1STSHTR7TDP1 | |
| SCHEMBL9564617 | 0.84 | HSD17B3 (0.66) | HSD17B3L3MBTL1STSHTR7TDP1 | |
| SCHEMBL9564653 | 0.84 | HSD17B3 (0.66) | HSD17B3L3MBTL1STSHTR7TDP1 | |
| SCHEMBL9564644 | 0.84 | HSD17B3 (0.66) | HSD17B3L3MBTL1STSHTR7TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114010631-A | Application of michelia lactone and derivatives thereof in treatment of traumatic craniocerebral injury | 上海市第六人民医院 | 2022-02-08 | — | — | CN | claimed |
| CN-105906591-A | Synthesis method of 2-amino-gamma-butyrolactone hydrochloride | 中国药科大学 | 2016-08-31 | — | — | CN | claimed |
| CN-102653543-A | Preparation method, biological activity and application of 3-substituted type Jolkinolide compound | UNIV CHINA PHARMA | 2012-09-05 | — | — | CN | claimed |
| US-6566359-B1 | For use as platelet- activating factor antagonists, inhibitors of certain protein kinases, transcriptional inhibitors of COX-2(cyclooxygenase-2) expression, and as agents in protecting brain tissue from injuries related to trauma | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2003-05-20 | — | — | US | claimed |
| EP-0830349-B1 | METHOD FOR PREPARING N, N'-DISUBSTITUED CYCLIC UREAS | DU PONT PHARM CO (US) | 2000-03-22 | — | — | EP | claimed |
| US-5877312-A | Method for preparing alkylating agents for their use for alkylating cyclic ureas | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-03-02 | — | — | US | claimed |
| EP-0830349-A1 | METHOD FOR PREPARING N, N'-DISUBSTITUED CYCLIC UREAS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-03-25 | — | — | EP | claimed |
| US-5637780-A | Method for preparing alkylating agents and their use for alkylating cyclic ureas | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-06-10 | — | — | US | claimed |
| EP-0767770-A1 | METHOD FOR PREPARING ALKYLATING AGENTS AND THEIR USE FOR ALKYLATING CYCLIC UREAS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-04-16 | — | — | EP | claimed |
| WO-1996039393-A1 | METHOD FOR PREPARING N, N'-DISUBSTITUED CYCLIC UREAS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-12 | — | — | WO | claimed |
| WO-1996000708-A1 | METHOD FOR PREPARING ALKYLATING AGENTS AND THEIR USE FOR ALKYLATING CYCLIC UREAS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-01-11 | — | — | WO | claimed |
| US-4716168-A | STIMULANTS OF IMMUNE RESPONSE | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1987-12-29 | — | — | US | claimed |
| EP-0187705-A2 | Imidazo(4,5-f)quinolines useful as immunomodulating agents | Norwich Eaton Pharmaceuticals, Inc. (US) | 1986-07-16 | — | — | EP | claimed |
| CN-114957357-A | Aminoglycoside derivatives and their use in the treatment of genetic disorders | ELOXX制药有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-110785233-A | Composite layered zeolite catalyst for conversion of heavy reformate to xylenes | 沙特阿拉伯石油公司 | 2020-02-11 | — | — | CN | disclosed |
| EP-2356979-B1 | ANTI-WRINKLE AGENTS | POLA CHEM IND INC (JP) | 2017-10-25 | — | — | EP | disclosed |
| EP-0083312-B1 | AQUEOUS BASED FIRE FOAM COMPOSITIONS CONTAINING HYDROCARBYL SULFIDE TERMINATED OLIGOMER STABILIZERS | CIBA-GEIGY AG (CH) | 1986-03-05 | — | — | EP | disclosed |
| US-4439329-A | Aqueous based fire fighting foam compositions containing hydrocarbyl sulfide terminated oligomer stabilizers | CIBA-GEIGY CORPORATION (US) | 1984-03-27 | — | — | US | disclosed |
| EP-0083312-A1 | Aqueous based fire foam compositions containing hydrocarbyl sulfide terminated oligomer stabilizers | CIBA-GEIGY AG (CH) | 1983-07-06 | — | — | EP | disclosed |
| US-4348410-A | Cyclohexane carboxylic acid derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1982-09-07 | — | — | US | disclosed |