Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | LAP3 | P28838 | 3/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4600642 | 0.83 | BCHE (0.54) | CYP1A2LAP3PTGS1SLC6A2MAOA | |
| SCHEMBL7599594 | 0.81 | TAAR1 (0.47) | EPHX1TAAR1MEN1KMT2ASLC6A2 | |
| SCHEMBL20504575 | 0.80 | MME (0.41) | TAAR1CYP2A6 | |
| SCHEMBL6239697 | 0.79 | EPHX1 (0.57) | EPHX1TAAR1MEN1KMT2ACYP1A2 | |
| SCHEMBL3051234 | 0.78 | SLC7A5 (0.46) | TAAR1MEN1KMT2ACYP1A2SLC7A5 | |
| SCHEMBL754753 | 0.78 | TRPA1 (0.41) | TAAR1MAOA | |
| SCHEMBL13754990 | 0.78 | ACE (0.45) | MEN1KMT2ACYP1A2ANPEPACE | |
| SCHEMBL10299126 | 0.78 | PPARG (0.38) | — | |
| SCHEMBL5949739 | 0.78 | TAAR1 (0.44) | TAAR1CYP1A2MAOASIGMAR1 | |
| SCHEMBL4952292 | 0.77 | EPHX1 (0.44) | EPHX1TAAR1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015193910-A1 | ASYMMETRIC SYNTHESIS OF 2-SUBSTITUTED INDOLINES AND 3-SUBSTITUTED CINNOLINES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-12-23 | — | — | WO | claimed |
| CN-101898944-B | Method for preparing alpha-bromo-cinnamaldehyde | WUHAN INST TECHNOLOGY | 2013-06-19 | — | — | CN | claimed |
| CN-101898944-A | Method for preparing alpha-bromo-cinnamaldehyde | WUHAN INST TECHNOLOGY | 2010-12-01 | — | — | CN | claimed |
| WO-2025091123-A1 | MESOIONIC CARBENES | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2025-05-08 | — | — | WO | disclosed |
| CN-114989173-B | Imidazole compound, pharmaceutical composition and application thereof | 广州市恒诺康医药科技有限公司 | 2024-03-19 | — | — | CN | disclosed |
| EP-3568390-B1 | SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INST (US) | 2024-03-06 | — | — | EP | disclosed |
| US-11806337-B2 | Small molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and uses thereof | Sanford Burnham Prebys Medical Discovery Institute (US) | 2023-11-07 | — | — | US | disclosed |
| US-11806337-B2 | Small molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and uses thereof | Sanford Burnham Prebys Medical Discovery Institute (US) | 2023-11-07 | — | — | US | disclosed |
| US-11806337-B2 | Small molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and uses thereof | Sanford Burnham Prebys Medical Discovery Institute (US) | 2023-11-07 | — | — | US | disclosed |
| US-20230116770-A1 | SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute | 2023-04-13 | — | — | US | disclosed |
| US-11452717-B2 | Small molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and uses thereof | Sanford Burnham Prebys Medical Discovery Institute (US) | 2022-09-27 | — | — | US | disclosed |
| US-5849261-A | Radiolabeled vasoactive intestinal peptides for diagnosis and therapy | DIATIDE, INC. (US) | 1998-12-15 | — | — | US | disclosed |
| WO-1998049196-A1 | CALCITONIN RECEPTOR-BINDING PEPTIDES | DIATIDE, INC. (US) | 1998-11-05 | — | — | WO | disclosed |
| EP-0820313-A2 | RADIOLABELED PEPTIDES FOR DIAGNOSIS AND THERAPY | Diatide, Inc. (US) | 1998-01-28 | — | — | EP | disclosed |
| EP-0804481-A1 | SOMATOSTATIN DERIVATIVES AND THEIR RADIOLABELLED PRODUCTS | Diatide, Inc. (US) | 1997-11-05 | — | — | EP | disclosed |
| EP-0775160-A1 | CYCLIC HEXAPEPTIDE SOMATOSTATIN ANALOGUES | DIATECH, INC. (US) | 1997-05-28 | — | — | EP | disclosed |
| US-5620675-A | MEDICAL DIAGNOSIS | DIATECH, INC. (US) | 1997-04-15 | — | — | US | disclosed |
| WO-1996030055-A2 | RADIOLABELED PEPTIDES FOR DIAGNOSIS AND THERAPY | DIATIDE, INC. (US) | 1996-10-03 | — | — | WO | disclosed |
| WO-1996004308-A1 | CYCLIC HEXAPEPTIDE SOMATOSTATIN ANALOGUES | DIATECH, INC. (US) | 1996-02-15 | — | — | WO | disclosed |
| WO-1995003330-A1 | SOMATOSTATIN DERIVATIVES AND THEIR RADIOLABELLED PRODUCTS | DIATECH, INC. (US) | 1995-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11452717-B2 | Small molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and uses thereof | NAMPT, NAPRT, NNT | EPHX1 3475/4885TAAR1 4669/4885MEN1 2154/4885 |
| US-11806337-B2 | Small molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and uses thereof | NAMPT, NAPRT, NNT | EPHX1 3475/4885TAAR1 4669/4885MEN1 2154/4885 |
| US-20230116770-A1 | SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF | NAMPT, NAPRT, NNT | EPHX1 3475/4885TAAR1 4669/4885MEN1 2154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.