SCHEMBL754753

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20504575	0.81	MME (0.41)	IDO1TAAR1TP53TSHRPPARG
	SCHEMBL10299126	0.79	PPARG (0.38)	TP53TSHRPPARGPPARA
	SCHEMBL3051234	0.79	SLC7A5 (0.46)	TAAR1
	SCHEMBL233264	0.78	EPHX1 (0.50)	TAAR1MAOA
	SCHEMBL8693276	0.78	TRPA1 (0.44)	TRPA1IDO1LOXL2CPA1LMNA
	SCHEMBL204959	0.75	TP53 (0.61)	TRPA1IDO1LOXL2CPA1LMNA
	SCHEMBL21439149	0.75	TP53 (0.61)	TRPA1IDO1LOXL2CPA1LMNA
	SCHEMBL2269305	0.75	LOXL2 (0.43)	TRPA1IDO1LOXL2CPA1TAAR1
	SCHEMBL12226226	0.75	TRPA1 (0.46)	TRPA1IDO1LOXL2CPA1LMNA
	SCHEMBL12809801	0.75	LOXL2 (0.43)	TRPA1IDO1LOXL2CPA1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.