Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2333026 | 0.78 | QPCT (0.37) | QPCTHCAR2DPP4HPGDTSHR | |
| SCHEMBL5056668 | 0.78 | QPCT (0.37) | QPCTHCAR2DPP4HPGDTSHR | |
| SCHEMBL2754283 | 0.78 | HCAR2 (0.37) | QPCTHCAR2DPP4HPGDTSHR | |
| SCHEMBL2334323 | 0.77 | LMNA (0.38) | DPP4HPGDTSHRGRM5 | |
| SCHEMBL30361116 | 0.77 | LMNA (0.38) | DPP4HPGDTSHRGRM5 | |
| SCHEMBL29868304 | 0.76 | QPCT (0.42) | QPCTHCAR2DPP4HPGDTSHR | |
| SCHEMBL15385182 | 0.76 | QPCT (0.42) | QPCTHCAR2DPP4HPGDTSHR | |
| SCHEMBL2335963 | 0.76 | GRM5 (0.36) | QPCTHCAR2DPP4HPGDTSHR | |
| SCHEMBL5135310 | 0.76 | QPCT (0.34) | QPCTHCAR2DPP4HPGDTSHR | |
| SCHEMBL1665578 | 0.75 | DPP4 (0.36) | HCAR2DPP4HPGDTSHRGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2533645-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | The Johns Hopkins University (US) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011100373-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | THE JOHNS HOPKINS UNIVERSITY (US) | 2011-08-18 | — | — | WO | disclosed |