Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HK1 | P19367 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29398181 | 0.84 | RAB9A (0.50) | ALDH1A1HSD17B10MAPTRAB9AHPGD | |
| SCHEMBL5162068 | 0.84 | ALDH1A1 (0.71) | ALDH1A1HSD17B10L3MBTL1RAB9AHPGD | |
| SCHEMBL5805651 | 0.84 | RAB9A (0.50) | ALDH1A1HSD17B10MAPTRAB9AHPGD | |
| SCHEMBL17727825 | 0.84 | IKBKB (0.46) | ALDH1A1HSD17B10MAPTRAB9AHPGD | |
| SCHEMBL29568495 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HSD17B10L3MBTL1MAPTRAB9A | |
| SCHEMBL30485727 | 0.82 | IKBKB (0.41) | ALDH1A1HSD17B10MAPTRAB9AHPGD | |
| SCHEMBL16173656 | 0.82 | RAB9A (0.48) | ALDH1A1HSD17B10MAPTRAB9AHPGD | |
| SCHEMBL2278862 | 0.80 | ALDH1A1 (0.52) | ALDH1A1HSD17B10MAPTRAB9AHPGD | |
| SCHEMBL6572513 | 0.80 | MEN1 (0.46) | ALDH1A1HSD17B10MAPTRAB9AHPGD | |
| SCHEMBL6011288 | 0.80 | KDM4E (0.46) | ALDH1A1HSD17B10MAPTRAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2662368-A1 | AROMATIC HETEROCYCLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME | Idemitsu Kosan Co., Ltd. (JP) | 2013-11-13 | — | — | EP | disclosed |
| EP-1856024-B2 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2011-08-17 | — | — | EP | disclosed |
| US-7772446-B2 | Method for producing substituted biphenyls | BASF SE (DE) | 2010-08-10 | — | — | US | disclosed |
| EP-1856024-B1 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2008-08-06 | — | — | EP | disclosed |
| US-20080183021-A1 | Method for Producing Substituted Biphenyls | BASF SE (DE) | 2008-07-31 | — | — | US | disclosed |
| EP-1856024-A1 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF AKTIENGESELLSCHAFT (DE) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006092429-A1 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF AKTIENGESELLSCAHFT (DE) | 2006-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080183021-A1 | Method for Producing Substituted Biphenyls | CBR3, DDT, HRH3 | ALDH1A1 2309/4885HSD17B10 880/4885L3MBTL1 1266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.