Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.38 |
| ▸ | MAP2 | P11137 | 1/20 | 0.30 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20568821 | 0.86 | GPR35 (0.43) | GPR35MAP2 | |
| SCHEMBL23351272 | 0.84 | GPR35 (0.39) | GPR35MAP2 | |
| SCHEMBL20569630 | 0.76 | GPR35 (0.56) | GPR35MAP2FBP1 | |
| SCHEMBL23327851 | 0.76 | GPR35 (0.38) | GPR35MAP2 | |
| SCHEMBL20568832 | 0.75 | CHEK1 (0.35) | GPR35 | |
| SCHEMBL23327639 | 0.75 | GPR35 (0.42) | GPR35 | |
| SCHEMBL23327553 | 0.75 | GPR35 (0.42) | GPR35MAP2 | |
| SCHEMBL23327722 | 0.74 | GPR35 (0.41) | GPR35MAP2 | |
| SCHEMBL23327816 | 0.74 | GPR35 (0.41) | GPR35MAP2 | |
| SCHEMBL23327571 | 0.71 | GPR35 (0.61) | GPR35MAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210137886-A1 | INHIBITORS OF METALLO-BETA-LACTAMASES | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2021-05-13 | — | — | US | claimed |
| US-20210137886-A1 | INHIBITORS OF METALLO-BETA-LACTAMASES | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2021-05-13 | — | — | US | disclosed |
| US-20210137886-A1 | INHIBITORS OF METALLO-BETA-LACTAMASES | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210137886-A1 | INHIBITORS OF METALLO-BETA-LACTAMASES | MGAM, GAA, LCT | GPR35 4727/4885MAP2 2432/4885FBP1 463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.