Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.57 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL956607 | 0.87 | SIGMAR1 (0.44) | SIGMAR1TMEM97HRH3 | |
| SCHEMBL958098 | 0.86 | SIGMAR1 (0.57) | SIGMAR1TMEM97HRH3DHODH | |
| Oxalic Acid SCHEMBL3567521 | 0.83 | SIGMAR1 (0.60) | SIGMAR1TMEM97HRH3HTR1ADRD2 | |
| SCHEMBL953780 | 0.81 | SIGMAR1 (0.83) | SIGMAR1TMEM97DHODHHTR1ADRD2 | |
| SCHEMBL958221 | 0.81 | SIGMAR1 (0.83) | SIGMAR1TMEM97DHODHHTR1ADRD2 | |
| SCHEMBL954667 | 0.80 | SIGMAR1 (0.51) | SIGMAR1TMEM97DHODH | |
| SCHEMBL955114 | 0.80 | SIGMAR1 (0.50) | SIGMAR1TMEM97 | |
| SCHEMBL954722 | 0.78 | SIGMAR1 (0.58) | SIGMAR1TMEM97HRH3HTR1ADRD2 | |
| SCHEMBL5170674 | 0.77 | SIGMAR1 (0.80) | SIGMAR1TMEM97HRH3HTR1ADRD2 | |
| Oxalic Acid SCHEMBL957526 | 0.77 | SIGMAR1 (0.75) | SIGMAR1TMEM97DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781619-B1 | SIGMA RECEPTOR INHIBITORS | ESTEVE LABOR DR (ES) | 2011-08-17 | — | — | EP | claimed |