Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.80 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL957621 | 0.89 | SIGMAR1 (1.00) | SIGMAR1TMEM97DRD2HTR1AHTR2A | |
| SCHEMBL954722 | 0.88 | SIGMAR1 (0.58) | SIGMAR1TMEM97DRD2HTR1AHTR2A | |
| Oxalic Acid SCHEMBL3567521 | 0.87 | SIGMAR1 (0.60) | SIGMAR1TMEM97DRD2HTR1AHTR2A | |
| Oxalic Acid SCHEMBL466885 | 0.85 | SIGMAR1 (0.90) | SIGMAR1TMEM97DRD2HTR1AHTR2A | |
| Oxalic Acid SCHEMBL956463 | 0.84 | SIGMAR1 (0.53) | SIGMAR1TMEM97CYP2D6 | |
| SCHEMBL8274349 | 0.80 | SIGMAR1 (0.80) | SIGMAR1TMEM97DRD2HTR1AHTR2A | |
| SCHEMBL3662631 | 0.79 | SIGMAR1 (0.50) | SIGMAR1TMEM97DRD2HTR1AHTR2A | |
| SCHEMBL8272461 | 0.78 | SIGMAR1 (0.48) | SIGMAR1TMEM97HTR1ATP53 | |
| SCHEMBL955900 | 0.78 | SIGMAR1 (0.77) | SIGMAR1TMEM97DRD2HTR1AHTR2A | |
| SCHEMBL958098 | 0.78 | SIGMAR1 (0.57) | SIGMAR1TMEM97HRH3TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781619-A1 | SIGMA RECEPTOR INHIBITORS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-05-09 | — | — | EP | claimed |
| WO-2006021463-A1 | SIGMA RECEPTOR INHIBITORS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-03-02 | — | — | WO | claimed |