Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 19/20 | 0.77 |
| ▸ | PRKD2 | Q9BZL6 | 10/20 | 0.59 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29897386 | 0.94 | PRKCZ (0.68) | PRKCZPRKD2 | |
| SCHEMBL23301044 | 0.94 | PRKCZ (0.68) | PRKCZPRKD2 | |
| SCHEMBL30175736 | 0.92 | PRKCZ (0.70) | PRKCZPRKD2 | |
| SCHEMBL23328154 | 0.92 | PRKCZ (0.70) | PRKCZPRKD2 | |
| SCHEMBL30175652 | 0.86 | PRKCZ (0.57) | PRKCZPRKD2 | |
| SCHEMBL30175633 | 0.86 | PRKCZ (0.57) | PRKCZPRKD2 | |
| SCHEMBL23328179 | 0.86 | PRKCZ (0.57) | PRKCZPRKD2 | |
| SCHEMBL23328171 | 0.86 | PRKCZ (0.57) | PRKCZPRKD2 | |
| SCHEMBL23328145 | 0.86 | PRKCZ (0.57) | PRKCZPRKD2 | |
| SCHEMBL23328341 | 0.84 | PRKCZ (0.55) | PRKCZPRKD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021084265-A1 | ISOQUINOLINE DERIVATIVES AS SIK2 INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2021-05-06 | — | — | WO | disclosed |